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http://dx.doi.org/10.1161/CIRCGEN.124.004603 | DOI Listing |
Int J Obes (Lond)
September 2025
West China Institute of Preventive and Medical Integration for Major Diseases, West China School of Public Health and West China Fourth Hospital, Sichuan University, Chengdu, Sichuan, China.
Background: The relationship between body mass index (BMI) and liver stiffness in older people remains unclear. This study aimed to examine the association between BMI and the risk of elevated liver stiffness in older people.
Methods: 2736 participants from the West China Health and Aging Cohort Study (WCHAC) were included in the present study.
Appl Radiat Isot
September 2025
Departamento de Física da Universidade Federal de Sergipe (DFI - UFS), Brazil; Programa de Pós-Graduação em Física, Universidade Federal de Sergipe (PPGFI - UFS), Brazil.
Angiography systems offer three dose rate modes (low, normal, and high) for performing fluoroscopy-guided interventional (FGI) procedures, with each mode corresponding to a specific set of parameters. Although the choice of mode should depend on the patient's biotype, such systems are typically shipped from the factory configured to start examinations in normal mode as the default. To reduce both the need for operator intervention during FGI procedures and the exposure of patients to ionizing radiation, we tested a change to the internal setup of an angiography machine in this study, in which the low-dose-rate mode was automatically selected as the default prior to starting a procedure.
View Article and Find Full Text PDFEur J Epidemiol
September 2025
Center of Clinical Big Data and Analytics of the Second Affiliated Hospital, School of Public Health, Zhejiang University School of Medicine, Hangzhou, 310058, China.
Previous studies on serum iron levels and mortality risk have yielded inconsistent findings based on single-point measurements. How serum iron levels and their longitudinal changes influence all-cause and cause-specific mortality remains unknown. This study investigated associations between baseline serum iron levels, their longitudinal changes, and all-cause and cause-specific mortality in a prospective cohort.
View Article and Find Full Text PDFInt J Mol Sci
August 2025
Department of Medical Biochemistry, Faculty of Pharmacy, University of Belgrade, 11000 Belgrade, Serbia.
Ankylosing spondylitis (AS) is a chronic inflammatory disease characterized by axial skeletal involvement and systemic metabolic changes. While inflammation is central to its pathophysiology, the potential role of thyroid hormones, particularly free triiodothyronine (FT3), in disease risk and activity remains underexplored. The objective of this study is to evaluate the relationship between serum FT3 levels and both the presence and clinical activity of AS, while also examining other endocrine-metabolic parameters.
View Article and Find Full Text PDFN Engl J Med
August 2025
Department of Cardiology, Heart Center, Rigshospitalet, University of Copenhagen, Copenhagen.
Background: Hypokalemia and even low-normal plasma potassium levels increase the risk of ventricular arrhythmias among patients with cardiovascular disease. An assessment of a strategy of actively increasing plasma potassium levels to the high-normal range is needed.
Methods: In this multicenter, open-label, event-driven, randomized superiority trial conducted in Denmark, we enrolled participants at high risk for ventricular arrhythmias (defined as those with an implantable cardioverter-defibrillator [ICD]) and with a baseline plasma potassium level of 4.