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http://dx.doi.org/10.3389/fgwh.2024.1365504 | DOI Listing |
Semin Nephrol
September 2025
University of Alabama at Birmingham, Department of Medicine, Division of Nephrology, Section of Cardio-Renal Physiology and Medicine, Birmingham, AL. Electronic address:
Chronic kidney disease of unknown etiology has been reported in Mesoamerican regions and other parts of the world, with increasing evidence pointing to heat stress as a central contributing factor. The incidence of acute kidney injury appears to correlate strongly with heat exposure, as demonstrated in both human and animal studies. The underlying mechanisms of heat-induced kidney injury are likely multifactorial, involving hemodynamic changes, immune responses, and possibly coagulopathies.
View Article and Find Full Text PDFAdv Drug Deliv Rev
September 2025
State Key Laboratory of Systems Medicine for Cancer, Shanghai Cancer Institute, Renji Hospital, School of Medicine, Shanghai Jiao Tong University, Shanghai 200032, China; Shanghai Key Laboratory of Cancer System Regulation and Clinical Translation, Jiading District Central Hospital, Renji Hospital J
DNA exhibits remarkable versatility, which is attributed to its inherent molecular recognition capabilities, programmable sequences, and excellent biocompatibility. Among its various topological forms, branched DNA (bDNA), including Y-shaped DNA (Y-DNA), X-shaped DNA (X-DNA), etc., stands out as a fundamental building block for fabricating functional DNA-based materials and has demonstrated great promise across diverse applications in recent years.
View Article and Find Full Text PDFInt J Biol Macromol
September 2025
State Key Laboratory of Advanced Technology for Materials Synthesis and Processing, Wuhan University of Technology, Wuhan, 430070, PR China. Electronic address:
Due to the poor regeneration ability of cartilage tissue, the design and fabrication of permanent hydrogel cartilage scaffolds with mechanical properties matching is still an urgent challenge. In this study, we propose an "inner swelling-outer restraint" strategy to construct Janus hydrogel for pressure-bearing cartilage replacement, which is inspired by the "Lamina-splendens" structure of cartilage. As a proof of concept, the poly(vinyl alcohol)/carboxymethyl cellulose sodium (PVA/CMCNa) layer is designed to capture more fluid by introducing negatively charged aggregates, while the macromolecular conformation of the PVA/MoS layer can be densified through wet annealing, thereby increasing the liquid permeation resistance of the PVA/CMCNa layer.
View Article and Find Full Text PDFJ Glob Antimicrob Resist
September 2025
Key Laboratory of Jilin Province for Zoonosis Prevention and Control, Changchun Veterinary Research Institute, Chinese Academy of Agriculture Sciences, Changchun, Jilin 130122, China. Electronic address:
Objectives: The usage of cephalosporins (CEFs) and co-existence of extended-spectrum β-lactamase (ESBL) gene bla in the same host may promote the prevalence of colistin (CST) resistance gene mcr-1. This study aims to investigate the underlying mechanisms how the mcr-1 and bla demonstrate significant co-occurrence in Escherichia coli (E. coli).
View Article and Find Full Text PDFLancet Child Adolesc Health
September 2025
Al-Quds University, Abu Dis, Palestine. Electronic address: