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Objective: This study aimed to investigate the features and underlying principles of acupuncture points used in the treatment of headaches associated with blood stasis syndrome.
Methods: Literature on the treatment of blood stasis headache with acupuncture and moxibustion was searched across three Chinese databases and one English database from January 1st, 2000, to January 1st, 2024. Relevant data including titles, journals, authors, keywords, interventions, main acupoints, and outcomes were extracted for further analysis.
Results: A total of 112 papers with 102 complete prescriptions were analyzed. Of the 77 acupoints examined, 72 were meridian points, and 5 were extraordinary points, used 699 times in total. The top ten acupoints by frequency were Fengchi (GB20), Taiyang (EX-HN5), Baihui (GV20), Hegu (LI4), Shuaigu (GB8), Taichong (LR3), Xuehai (SP10), Touwei (ST8), Geshu (BL17), and Waiguan (TE5). Yang meridian points were used more frequently than Yin meridian points (82.8% vs 17.2%), with the Gallbladder Meridian of Foot Shaoyang being the most common. Nearly half of the acupoints (49.9%) were on the head and neck, and 23.1% on the lower limbs. Specific acupoints accounted for 53.5% of the total frequency. Fengchi (GB20) and Taiyang (EX-HN5) showed the highest correlation. Association rule mining highlighted combinations like Fengchi (GB20) with Taiyang (EX-HN5) and Baihui (GV20). Cluster analysis yielded five clusters.
Conclusion: The study provides insights into selecting effective acupoints and combinations for clinical acupuncture practice and experimental studies in treating blood stasis headaches. Acupoints like Fengchi (GB20), Taiyang (EX-HN5), and Baihui (GV20) may be effective for clinical treatment, but further studies are needed to validate their efficacy.
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http://dx.doi.org/10.2147/JPR.S471441 | DOI Listing |
Am J Case Rep
September 2025
Department of Ophthalmology, University Medical Center Ljubljana, Ljubljana, Slovenia.
BACKGROUND Central retinal vein occlusion (CRVO) is associated with cardiovascular risk factors, but hypercoagulability, endothelial dysfunction, and stasis of blood present in patients with chronic obstructive pulmonary disease (COPD) may also play a role in its pathogenesis. This report describes the case of a 70-year-old woman who presented with reduced vision in the right eye due to CRVO. CASE REPORT A 70-year-old woman with a history of smoking presented with decreased vision in the right eye.
View Article and Find Full Text PDFJ Pept Sci
October 2025
School of Chinese Materia Medica, Beijing University of Chinese Medicine, Beijing, China.
Targeting thrombin to screen safe thrombin inhibitors from natural plants and animals is a critical direction in anticoagulant drug development. This study aimed to screen thrombin inhibitors from the nonbloodsucking leech Whitmania pigra (WP) and elucidate the mechanism of anticoagulation through a "computation-guided experimentation" strategy. A peptide library was constructed from WP hydrolysates, and virtual screening was performed using molecular docking and dynamics simulations.
View Article and Find Full Text PDFJ Physiol
September 2025
Undergraduate Medical Education, Cumming School of Medicine, University of Calgary, Calgary, AB, Canada.
Hum Vaccin Immunother
December 2025
Chinese Medicine Research Center, China Medical University, Taichung, Taiwan.
Traditional Chinese Medicine (TCM) classifies individuals into constitution types that may influence physiological responses. SARS-CoV-2 vaccines induce spike-specific antibodies and activate B and T cells, including memory subsets. This study investigates whether TCM constitution types are associated with immune responses and adverse events following COVID-19 vaccination.
View Article and Find Full Text PDFJ Ethnopharmacol
September 2025
Pingshan Hospital, Southern Medical University, Shenzhen, Guangdong 518118, P.R. China; Pingshan District Peoples' Hospital of Shenzhen, Shenzhen, Guangdong 518118, P.R. China; School of Traditional Chinese Medicine, Southern Medical University, Guangzhou, Guangdong 510515, China. Electronic address
Ethnopharmacological Relevance: Dingxin Recipe III (DXRIII) is a traditional Chinese medicinal formulation that has been employed in clinics for over two decades. It is utilized in the treatment of cardiovascular diseases associated with atherosclerosis (AS) through mechanisms purported to involve the clearing of heat and detoxification, as well as the promotion of blood circulation and the removal of blood stasis. Despite its widespread application and reported therapeutic benefits, its exact mechanisms remain incompletely elucidated.
View Article and Find Full Text PDF