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Introduction: The transition of experience from unconscious to conscious, the emergent process, is a crucial topic in consciousness studies. Three frameworks exist to explain the process: (1) consciousness arises in an all-or-none manner; (2) consciousness arises gradually; (3) consciousness arises either all at once or gradually, depending on the level of stimulus processing (low- vs. high-level). However, the development of emergent processes of consciousness remains unclear. This study examines the development of emergent processes of consciousness based on the level of stimulus processing framework.
Methods: Ninety-nine children (5-12 year-olds) and adults participated in two online discrimination tasks. These tasks involved color discrimination as lower-level processing and number magnitude discrimination as higher-level processing, as well as backward masking with stimulus onset asynchronies (SOAs) varying from 16.7 to 266.7 ms. We measured objective discrimination accuracy and used a 4-scale Perceptual Awareness Scale (PAS) to assess subjective awareness. We fit the data to a four-parameter nonlinear function to estimate the center of the slope (threshold) and the range of the slope (gradualness, the measure of emergent process of consciousness) of the model.
Results: The results showed the threshold of objective discrimination was significantly higher in 5-6 year-olds than in 7-12 year-olds, but not of subjective awareness. The emergent process of objective discrimination in the number task was more gradual than in the color task.
Discussion: The findings suggest that the thresholds of subjective awareness in 5-6 year-olds and objective discrimination in 7-9 year-olds are similar to those in adults. Moreover, the emergent processes of subjective awareness and objective discrimination in 5-6 year-olds are also similar to those in adults. Our results support the level of processing hypothesis but suggest that its effects may differ across developmental stages.
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http://dx.doi.org/10.3389/fpsyg.2024.1337589 | DOI Listing |
Int J Gen Med
September 2025
Department of Gynecology, Zhongshan Hospital, Fudan University, Shanghai, 200035, People's Republic of China.
Objective: This study aims to investigate the association between the dynamics of routine metabolic markers and endometriosis severity.
Methods: A retrospective analysis was conducted on patients diagnosed with endometriosis at Zhongshan Hospital, Xiamen, affiliated with Fudan University. The collected data encompassed demographic details and biochemical indicators related to lipid, hepatobiliary, renal metabolism, and electrolyte balance.
Int J Gen Med
September 2025
School of Public Health, Bengbu Medical University, Bengbu, People's Republic of China.
Objective: To develop and validate a nomogram model for predicting the risk of hyperuricemia (HUA) in perimenopausal women.
Methods: In this study, physical examination information of perimenopausal women was collected at the First Affiliated Hospital of University of Science and Technology of China. We utilized the Least Absolute Shrinkage and Selection Operator (Lasso) and binary logistic regression to investigate the risk factors of HUA among perimenopausal women.
Front Oncol
August 2025
Department of Colorectal Surgery, National Cancer Center/National Clinical Research Center for Cancer/Cancer Hospital, Chinese Academy of Medical Sciences and Peking Union Medical College, Beijing, China.
Objective: The retrieval of 12 lymph nodes (LNs) remains a crucial criterion for accurate staging and prognosis evaluation in rectal cancer (RC). However, some patients fail to meet this threshold after surgery. This study developed a nomogram model based on clinical variables to predict the probability of retrieving 12 LNs postoperatively.
View Article and Find Full Text PDFSouth Afr J Crit Care
May 2025
Department of Paediatrics and Child Health, Faculty of Health Sciences, University of the Free State, Bloemfontein, South Africa.
Background: Procalcitonin (PCT) is used in the diagnosis of sepsis. Its capability as a prognostic marker is unclear. The association between PCT and paediatric intensive care unit (PICU) outcomes has not been investigated in the South African setting.
View Article and Find Full Text PDFFront Cell Neurosci
August 2025
Stem Cell Research Center, University of California, Irvine, Irvine, CA, United States.
Objective: To assess the safety and tolerability of intravitreal injection of human retinal progenitor cells (RPCs) at multiple dose levels in adults with non-syndromic retinitis pigmentosa (RP).
Design: A prospective, multicenter, open-label, single-arm, Phase I/IIa safety study of RPCs in adults with RP ( = 28). Two patient cohorts were studied: Cohort 1: BCVA no better than 20/200 and no worse than Hand Motions, and Cohort 2: BCVA no better than 20/40 and no worse than 20/200).