Category Ranking
98%
Total Visits
921
Avg Visit Duration
2 minutes
Citations
20
Article Abstract
Hand, foot, and mouth disease (HFMD) is a common infectious disease caused by enteroviruses. Coxsackievirus A6 (CV-A6)-associated HFMD has recently emerged as a predominant disease worldwide. Here, we describe five HFMD cases caused by CV-A6 in Japan from 2019 to 2022. All clinical courses were not severe and were self-limited, and the skin exanthema with vesicles differed from that in classical HFMD. Phylogenetic analysis showed that the major epidemic strain cluster of CV-A6 was formed independently in 2011, and our latest CV-A6 strains in Japan were detected within this cluster. The five cases described in this report indicate the recent shift in the predominant and continuous disease manifestation of CV-A6-associated HFMD.
Download full-text PDF |
Source |
|---|---|
| http://www.ncbi.nlm.nih.gov/pmc/articles/PMC11270346 | PMC |
| http://dx.doi.org/10.3390/idr16040044 | DOI Listing |
Publication Analysis
Top Keywords
Similar Publications
Idmatch Bike Fitting Enhances Power Output in Recreational Cyclists: A Pilot Study.
Int J Exerc Sci
September 2025
Department of Health and Human Performance, University of Wisconsin-River Falls, River Falls, WI, USA.
Optimizing bike position is essential for enhancing cycling performance, improving comfort, and reducing injury risk. This study examined the acute effects of a bike fit using the idmatch system on power output, rate of perceived exertion (RPE), and discomfort in recreational cyclists. Twelve participants (10 males, 2 females; 37.
View Article and Find Full Text PDFDe Novo GLI2 Missense Variant in a Child With Isolated Hypopituitarism and Craniofacial Anomalies: Expanding the Phenotypic Spectrum.
Mol Genet Genomic Med
September 2025
Genomic Health, West Leederville, Western Australia, Australia.
Background: Culler-Jones syndrome (CJS) is an autosomal dominant disorder characterized by hypopituitarism, postaxial polydactyly, and craniofacial anomalies, associated with pathogenic GLI2 variants. Genotype-phenotype correlations suggest missense variants may present with isolated pituitary phenotypes.
Methods: We evaluated an 8-year-old boy referred for short stature, failure to thrive, and neurodevelopmental concerns.
Design and implementation of a writing-stroke motor imagery paradigm for multi-character EEG classification.
Neuroscience
September 2025
College of Electrical and Control Engineering, Xi'an University of Science and Technology, Xi'an 710054, China; Xi'an Key Laboratory of Electrical Equipment Condition Monitoring and Power Supply Security., Xi'an 710054, China.
Motor imagery (MI) based brain-computer interfaces (BCI) decode neural activity to generate command outputs. However, the limited number of distinguishable commands in traditional MI-BCI systems restricts practical applications. To overcome this limitation, we propose a multi-character classification framework based on Electroencephalography (EEG) signals.
View Article and Find Full Text PDFDevelopment of disease-specific growth charts for Argentine Prader-Willi syndrome without growth hormone treatment.
Ann Hum Biol
December 2025
Growth and Development Department, Hospital de Pediatría J.P. Garrahan, Buenos Aires, Argentina.
Background: Prader-Willi syndrome (PWS) is a complex genetic disorder characterised by infantile hypotonia, early-onset obesity, intellectual disability, hypopigmentation, small hands and feet, short stature, hypogonadism, and distinctive facial features.
Aim: To generate and report growth curves for height, sitting height, hands and feet length for Argentine children with Prader-Willi syndrome (PWS) without growth hormone treatment.
Subjects And Methods: A total of 1174 anthropometric measures were obtained from 167 children (82 boys) aged 0-19 years attending Hospital Garrahan between 1992 and 2019.
Determination of 5-Fluorouracil in Dried Blood Spots for Therapeutic Drug Monitoring and Adverse Event Assessment in Breast Cancer Patients.
Clin Pharmacol
August 2025
Dharmais Cancer Hospital, Jakarta, 11420, Indonesia.
Background: 5-Fluorouracil (5-FU) is a chemotherapy drug used to treat breast cancer. Monitoring 5-FU levels in blood is essential due to its narrow therapeutic range, high individual variability, nonlinear pharmacokinetics, dosage calculations based on body surface area, and susceptibility to toxicity influenced by individual factors such as enzyme polymorphisms.
Methods: An observational study was conducted in 2 types of patients: patients receiving intravenous 5-FU chemotherapy and those receiving oral chemotherapy with capecitabine as the 5-FU prodrug.