98%
921
2 minutes
20
Using data from two ED. departments of 773 patients admitted with SARS-CoV-2, ICD-10 codes derived from the General Practitioner - Summary Care Record (GP-SCR) and Emergency Department (ED.) records were analysed for code discrepancies and whether this related to increased mortality. The average number of ICD-10 codes in both GP-SCR and ED. records was higher for patients who died than patients who survived (all < .0001). Pre-existing GP digital data provides a better prediction of mortality than data collected manually during admission clerking in the ED. Up to 78.47% of GP-SCR codes were missed in the ED. records and up to 45.49% of the ED. record codes were not in the GP-SCR. A subset of missed ICD-10 codes were identified as being able to predict outcome; a trend towards increasing death rate as the proportion of missed codes increases. Initiatives to make the GP-SCR available to the wider healthcare community should improve patient care and reduce bias during development of machine learning based algorithms.
Download full-text PDF |
Source |
---|---|
http://dx.doi.org/10.1177/14604582241249929 | DOI Listing |
J Intensive Care Med
September 2025
Independent Researcher, Outcomes Research, Atlanta, GA, USA.
Purpose: Obesity is a risk factor for sepsis complications in older adults. We assessed the impact of metabolically healthy obesity (MHO) and metabolically unhealthy obesity (MUHO) on outcomes in septic shock.
Methods: We conducted a retrospective analysis using the National Inpatient Sample (2016-2020) to identify a cohort of 1,737,075 patients aged 65 years and older who were hospitalized with septic shock, as defined by ICD-10 diagnosis codes.
Dis Colon Rectum
September 2025
Division of Colon and Rectal Surgery, Beth Israel Deaconess Medical Center, Harvard Medical School.
Background: Individuals born with anorectal and pelvic malformations require lifelong management. Although initially cared for by pediatric providers, these conditions continue to impact patients' health and quality of life into adulthood.
Objective: To assess the prevalence of psychiatric disorders and substance use among adults with congenital colorectal and pelvic malformations, and to explore their distribution across demographic and clinical variables.
Diabetes Obes Metab
September 2025
Epidemiology, IQVIA, Frankfurt, Germany.
Aims: To examine the association between elevated body mass index (BMI) and a wide range of vascular and cardiometabolic diseases in men and women.
Materials And Methods: This retrospective cohort study used data from the IQVIA Disease Analyzer database, comprising anonymized records from over 3000 office-based physicians in Germany. We included 233 730 patients aged ≥40 years with at least one recorded BMI measurement between January 2005 and December 2023.
Ophthalmol Sci
July 2025
Department of Ophthalmology, Hadassah Medical Organization and Faculty of Medicine, Hebrew University of Jerusalem, Jerusalem, Israel.
Objective: To examine whether there is an association between age-related macular degeneration (AMD) and dementia using a large, multi-institutional clinical data.
Design: A retrospective cohort study.
Participants: Patients with AMD, including both neovascular AMD (nvAMD) and non-neovascular AMD (non-nvAMD) types, along with matched controls who had a record of eye examination but no diagnosis of AMD.
Clin Epidemiol
September 2025
Department of Clinical Epidemiology, Department of Clinical Medicine, Center for Population Medicine, Aarhus University and Aarhus University Hospital, Aarhus, Denmark.
Purpose: To estimate the positive predictive value (PPV) of case ascertainment algorithm for hypocalcemia leading to hospitalization or emergency visit in the Swedish National Patient Register among women with postmenopausal osteoporosis (PMO) treated with antiresorptive agents. This was a regulator-requested validation study to support a multidatabase postauthorisation safety study (PASS) of antiresorptive treatment.
Methods: The Swedish part of the PASS was based on data from Swedish population registries.