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http://dx.doi.org/10.1093/jac/dkae201 | DOI Listing |
Crit Care Explor
June 2025
Centre for Heart Lung Innovation, St. Paul's Hospital, University of British Columbia, Vancouver, BC, Canada.
Objectives: Hospitalized community-acquired pneumonia (CAP) patients are admitted for ventilation, vasopressors, and renal replacement therapy (RRT). This study aimed to develop a machine learning (ML) model that predicts the need for such interventions and compare its accuracy to that of logistic regression (LR).
Design: This retrospective observational study trained separate models using random-forest classifier (RFC), support vector machines (SVMs), Extreme Gradient Boosting (XGBoost), and multilayer perceptron (MLP) to predict three endpoints: eventual use of invasive ventilation, vasopressors, and RRT during hospitalization.
Br J Anaesth
May 2025
College of Integrated Traditional Chinese and Western Medicine, Southwest Medical University, Luzhou, China; Department of Traditional Chinese Medicine, The Affiliated Hospital, Southwest Medical University, Luzhou, China. Electronic address:
Intern Emerg Med
August 2025
Department of Chest Disease, Ankara University School of Medicine, Ankara, Turkey.
JAMA Pediatr
March 2025
Department of Pediatrics, Children's Hospital of Eastern Ontario, University of Ottawa, Ottawa, Ontario, Canada.
Importance: Detection of congenital cytomegalovirus (cCMV) infection has previously relied on targeted screening programs or clinical recognition; however, these approaches miss most cCMV-infected newborns and fail to identify those infants who are asymptomatic at birth but at risk for late-onset sensorineural hearing loss.
Objective: To determine the feasibility of using routinely collected newborn dried blood spots (DBS) in a population-based cCMV screen to identify infants at risk for hearing loss and describe outcomes of infants screened.
Design, Setting, And Participants: This diagnostic study of a population-based screening program in Ontario, Canada, took place from July 29, 2019, to July 31, 2023.
Front Pediatr
December 2024
Thai Binh University of Medicine and Pharmacy, Thai Binh, Vietnam.