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The block design test (BDT) has been used for over a century in research and clinical contexts as a measure of spatial cognition, both as a singular ability and as part of more comprehensive intelligence assessment. Traditionally, the BDT has been scored using methods that do not reflect the full potential of individual differences that could be measured by the test. Recent advancements in technology, including eye-tracking, embedded sensor systems, and artificial intelligence, have provided new opportunities to measure and analyze data from the BDT. In this methodological review, we outline the information that BDT can assess, review several recent advancements in measurement and analytic methods, discuss potential future uses of these methods, and advocate for further research using these methods.
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http://dx.doi.org/10.3390/jintelligence12060053 | DOI Listing |
J Immigr Minor Health
September 2025
Melbourne School of Population and Global Health, University of Melbourne, Melbourne, Australia.
Wellbeing is a widely used concept yet lacks a universal definition and standardized measurement. Migrants, especially those forcibly displaced, face challenges that impact their quality of life and wellbeing. To understand how the wellbeing of people who migrate from low/middle-income countries to middle/high-income countries has been conceptualized, defined, and measured.
View Article and Find Full Text PDFJACC Basic Transl Sci
September 2025
BHF Centre for Cardiovascular Science, Queens Medical Research Institute, University of Edinburgh, Edinburgh, United Kingdom; Department of Pathology, Cardiovascular Research Institute Maastricht (CARIM), Maastricht University Medical Centre, Maastricht, the Netherlands. Electronic address: andy.bak
Coronary artery bypass graft (CABG) surgery remains the gold standard of care to prevent myocardial ischemia in patients with advanced atherosclerosis; however, poor long-term graft patency remains a considerable and long-standing problem. Excessive vascular smooth muscle cell (SMC) proliferation in the grafted tissue is recognized as central to late CABG failure. We previously identified SMILR, a human-specific SMC-enriched long noncoding RNA that drives SMC proliferation, suggesting that targeting SMILR expression could be a novel way to prevent neointima formation, and thus CABG failure.
View Article and Find Full Text PDFAcc Chem Res
September 2025
Department of Chemistry, University of British Columbia, 2036 Main Mall, Vancouver, British Columbia V6T 1Z1, Canada.
ConspectusHydroaminoalkylation, the catalytic addition of amines to alkenes, has evolved as a powerful tool in modern synthetic chemistry, offering an atom-economic and green approach to the construction of C-C bonds. This reaction enables the direct amine functionalization of alkenes and alkynes without the need for protecting groups, directing groups, or prefunctionalization, thereby eliminating stoichiometric waste and minimizing synthetic steps. Over the past two decades, significant advances in catalyst development and mechanistic understanding have expanded the scope of hydroaminoalkylation, allowing for control over regio-, diastereo-, and enantioselectivity.
View Article and Find Full Text PDFFront Neurosci
August 2025
Department of Health Sciences, Universidade Estadual de Santa Cruz, Ilhéus, Brazil.
Introduction: Studies suggest that serotonin (5-HT) plays an important role in alcohol use disorder (AUD). While several receptor subtypes modulate the role of 5-HT in AUD, evidence suggests that 5-HT and 5-HT receptors may be directly involved in alcohol drinking due to their interaction with the mesolimbic dopaminergic system. The aim of the present study was to investigate the effects of 5-HT and 5-HT antagonists, alone or in combination, on the acquisition and expression (i.
View Article and Find Full Text PDFTransl Anim Sci
August 2025
Department of Animal Science, South Dakota State University, Brookings, SD 57007, USA.
This experiment evaluated the effects of replacing one-third of corn grain in a finishing diet with rye grain (RG) processed using one of three processing methods. Predominately Angus steers (n = 192, initial shrunk BW = 410 ± 20.9 kg) were blocked by source and pen location and assigned to one of four dietary treatments: dry-rolled corn (DRC), unprocessed RG (UNP), dry-rolled RG (DRR) and hammer-milled RG (HMR).
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