98%
921
2 minutes
20
Background: Very early bilateral cochlear implant (CI) provision is today's established standard for children. Therefore, the assessment of preverbal and verbal performance in very early stages of development is becoming increasingly important. Performance data from cohorts of children were evaluated and presented based on diagnostic assessment using chronological age (CA) and hearing age (HA).
Methods: The present study, as part of a retrospective multicentre study, included 4 cohorts (N = 72-233) of children with bilateral CI without additional disabilities. Their results in the German parent questionnaires Elternfragebögen zur Früherkennung von Risikokindern(ELFRA‑1 and ELFRA-2) subdivided for CA and HA were statistically analysed. The data were also analysed in terms of mono-/bilingualism and age at CI provision.
Results: Overall, verbal performance in relation to CA was lower than in relation to HA. Preverbal skills were largely CA appropriate. Children with bi-/multilingual language acquisition performed significantly lower. Verbal performance in ELFRA‑2 referenced to CA was negatively correlated with age at CI provision.
Conclusion: In the case of early CI provision, CA should be the preferred reference mark in preverbal and verbal assessment in order to obtain exact individual performance levels and avoid bias in results. The percentiles determined are of limited use as generally valid reference values to which the individual performance of bilaterally implanted children could be compared. Further multicentre studies should be initiated.
Download full-text PDF |
Source |
---|---|
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC12021935 | PMC |
http://dx.doi.org/10.1007/s00106-024-01489-w | DOI Listing |
Ann Clin Transl Neurol
September 2025
Department of Neuroscience, Psychology, Drug Research and Child Health, University of Florence, Florence, Italy.
Background: Plasma p-tau181 has proven to be a promising diagnostic and prognostic tool in the earliest phases of Alzheimer's disease (AD). We aimed to evaluate the prognostic role of p-tau181 in predicting conversion to AD dementia and worsening in cognition in mild cognitive impairment (MCI) and subjective cognitive decline (SCD).
Methods: We consecutively enrolled 163 patients (50 SCD, 70 MCI, and 43 AD-demented (AD-d)), who underwent plasma p-tau181 analysis with the Simoa assay.
J Cogn Dev
March 2025
Department of Communicative Sciences and Disorders, New York University, 665 Broadway, New York, New York 10012.
This research paper explores the role of speaker, listener and real-time social attention for pronoun comprehension in autistic and nonautistic children in northeast United States. We assessed the pronoun comprehension of 22 autistic children (average age of 62 months, range 46-80 months) and 22 nonautistic children (average age 44 months, range 30-57 months) matched on expressive vocabulary scores. We evaluated first- and second-person possessive pronoun comprehension ("my" and "your") using a game in which two experimenters hid stickers and provided clues to their location by providing a verbal clue (e.
View Article and Find Full Text PDFBMC Public Health
September 2025
The Child Health Care Service, Region Jönköping County, Jönköping, Sweden.
Background: The first year of a child's life is essential for promoting a healthy life, and the transition to becoming a parent can be a challenge; parents need to develop confidence in their own capacity to care for their child. The national Child Health Services programme in Sweden offers parental support, both on a universal level and in accordance with the individual family's needs. This study explores parents' experiences of an extended home-visit programme offered through a Family Centre to all first-time parents in a municipality.
View Article and Find Full Text PDFPsychogeriatrics
September 2025
Department of Psychiatry, The 4th People's Hospital of Ziyang, Ziyang Psychosis Hospital, Ziyang, China.
Background: Olfactory training (OT) has been proposed as a non-pharmacological intervention to improve cognitive functions and depressive symptomatology, but evidence remains fragmented.
Methods: In this study, we conducted a systematic review and meta-analysis of randomised controlled trials (RCTs) comparing OT versus control in middle-aged and elderly adults. Four databases (PubMed, Cochrane Library, Web of Science, Embase) were systematically searched from database inception through June 2025.
Brain Res Bull
September 2025
Department of Neurology, The Second Affiliated Hospital of Anhui Medical University, 230601, He Fei, China; Collaborative Innovation Center of Neuropsychiatric Disorders and Mental Health, 230032, Hefei, China; Anhui Province Key Laboratory of Cognition and Neuropsychiatric Disorders, 230032, Hefei,
Background: The relationships between white matter microstructure, cortical atrophy, and cognitive function in cerebral small vessel disease (CSVD)-related white matter hyperintensities (WMHs) patients are unclear.
Methods: 71 right-handed WMHs patients (mild, n=23; moderate, n=27; severe, n=21) and 35 healthy controls were included. Tract-based spatial statistics (TBSS) assessed microstructure via fractional anisotropy (FA) and mean diffusivity (MD).