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Purpose: This study aimed to assess the relationship between A Body Shape Index (ABSI) and cognitive impairment among older adults in the United States.
Methods: This cross-sectional study analyzed cognitive function in 2,752 individuals aged 60 and older using data from the 2011-2014 National Health and Nutrition Examination Survey (NHANES). Cognitive assessments were conducted using the Immediate Recall Test (IRT), Delayed Recall Test (DRT), Animal Fluency Test (AFT), and Digit Symbol Substitution Test (DSST). A Body Shape Index (ABSI) was calculated from waist circumference (WC), weight, and height. The relationship between ABSI and cognitive outcomes was examined through multifactorial linear regression, smooth curve fitting, and subgroup and interaction analyses.
Results: With complete data, 2752 persons 60 and older participated in the study. After adjusting for covariables, these results showed statistically significant negative relationships between ABSI, IRT, and DSST scores. The negative correlation between DSST and ABSI is more substantial in males than females. There is less of a negative link between ABSI, AFT, and DSST among drinkers who consume 12 or more drinks annually compared to those who consume less. Furthermore, compared to individuals without high blood pressure(HBP), those who suffered HBP showed a more significant negative connection between ABSI and AFT.
Conclusion: Lower cognitive function was linked to higher ABSI.
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http://dx.doi.org/10.1186/s12944-024-02165-2 | DOI Listing |
Food Funct
September 2025
College of Food Science, Southwest University, Chongqing, 400715, China.
Bifidobacteria are naturally found in the human gut and quickly establish dominance shortly after birth, playing a crucial role in the development and stability of the infant gut microbiota. A growing body of research suggests that host and environmental factors shape the colonization and the relative abundance of bifidobacteria in the infant gut during early life. Understanding the factors that influence bifidobacterial colonization and maintaining normal colonization levels are keys to ensuring gut health.
View Article and Find Full Text PDFJ Morphol
September 2025
School of Agriculture, Biomedicine and Environment, La Trobe University, Melbourne, Victoria, Australia.
Although the surface micro-ornamentation of the scales within the skin of snakes has been the subject of many previous studies, there has been little work done on the spectacle, a protective (keratinised) goggle separated from the underlying cornea by a sub-spectacular space. The surface ultrastructure of the "Oberhäutchen" of the spectacle is examined in nine species of snakes (five aquatic and four terrestrial) using light and electron microscopy, micro-computed tomography and gel-based profilometry. Significant topographic differences in cell size (increases of between 5.
View Article and Find Full Text PDFInt J Eat Disord
September 2025
Department of Emergency Psychiatry and Acute Care, Lapeyronie Hospital, Montpellier, France.
Objective: This study compared overvaluation of weight and shape (OWS), drive for thinness (DT), and their combination (OWS-DT) as alternative severity classifications for anorexia nervosa (AN) to the fifth edition of the Diagnostic and Statistical Manual of Mental Disorders (DSM-5) severity classification.
Method: 312 AN treatment-seeking outpatients (mean age = 26.8, SD = 10.
Mol Ther
September 2025
Sanofi, Waltham, MA, USA.
Since its use during the COVID-19 pandemic, mRNA has emerged as a leading candidate vaccine platform for pandemic infections. A critical difference between RNA-encoded antigen and protein vaccines is that RNA-based vaccines require the antigen to be translated in the body, adding an important variable. Much of the research focus in the field has been on ways to increase expression, but inflammation plays a critical role.
View Article and Find Full Text PDFEarly Hum Dev
September 2025
Child Growth & Anthropology Unit, Department of Pediatrics, Postgraduate Institute of Medical Education & Research (PGIMER), Chandigarh, India. Electronic address:
Objectives: This study aimed to examine physical and craniofacial growth patterns in preschool-aged children with microcephaly and evaluate their potential clinical significance.
Methods: A total of 130 children (76 boys, 54 girls) aged 1-5 years with microcephaly (head circumference <-3 standard deviations) were enrolled in this prospective study at a tertiary care hospital, with 130 age- and sex-matched healthy controls. Nine craniofacial dimensions (head circumference, head length, head width, physiognomic facial length, morphological facial length, minimum frontal diameter, bizygomatic diameter, bigonial diameter, and total jaw height) were measured every six months using standardized techniques and instruments.