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http://dx.doi.org/10.1093/ehjcr/ytae252 | DOI Listing |
Eur J Anaesthesiol
September 2025
From the Department of Anesthesiology and Pain Medicine, Seoul National University Hospital, Seoul National University College of Medicine, Seoul, Republic of Korea (J-HL, J-BP, S-HJ, Y-EJ, E-HK, J-TK, H-SK).
Background: Arterial catheterisation is a critical procedure in paediatric patients undergoing surgery; however, it poses certain risks. Complications such as thrombus formation, arterial stenosis and haematoma may occur, yet their true incidence and contributing factors remain incompletely understood.
Objective: To assess the incidence of complications and identify associated risk factors following radial arterial catheterisation in paediatric patients.
Background: In the presence of a potent P2Yinhibitor such as prasugrel, the additional clinical antithrombotic benefit of aspirin is unclear. The feasibility of prasugrel monotherapy without aspirin after percutaneous coronary intervention (PCI) has been demonstrated in chronic coronary syndrome, but is yet to be assessed in patients with non-ST elevation acute coronary syndrome (NSTE-ACS) and low anatomical complexity.
Methods And Results: ASET-Japan is a single-arm study investigating the safety of prasugrel 12-month monotherapy with a locally approved dose (loading 20 mg; maintenance 3.
Sao Paulo Med J
September 2025
Physician, Departamento de Obstetrícia, Hospital Universitário Pedro Ernesto, Universidade do Estado do Rio de Janeiro (UERJ), Rio de Janeiro (RJ), Brazil.
Background: Pregnant women are at an increased risk of thromboembolism compared with non-pregnant women. Venous thrombosis is a manifestation of antiphospholipid syndrome (APS), an autoimmune thrombophilia associated with pregnancy morbidity.
Objectives: This study was designed to compare gestational outcomes of pregnant patients with deep venous thrombosis (DVT) and primary APS with outcomes of patients with DVT and negative results for antiphospholipid antibodies (aPLs).
A A Pract
September 2025
From the Department of Anesthesiology, Northwestern Medicine, Feinberg School of Medicine, Chicago, Illinois.
Bleeding is common after cardiac surgery and is associated with increased morbidity and mortality. The etiology of coagulopathy after cardiopulmonary bypass is complex, involving systemic inflammation, hemodilution, residual heparin effect, platelet activation, hypothermia, and hyperfibrinolysis. Antifibrinolytic agents such as aprotinin and lysine analogs are used to mitigate hyperfibrinolysis.
View Article and Find Full Text PDFThromb Haemost
September 2025
School of Biomedical Engineering and Imaging Sciences, King's College London, United Kingdom, London, United Kingdom of Great Britain and Northern Ireland.
The left atrium (LA) is particularly susceptible to blood stasis in conditions like atrial fibrillation (AF), which can lead to thrombus formation, especially in the left atrial appendage (LAA). Spontaneous echo contrast (SEC) in the LA, detectable via transoesophageal echocardiography (TEE), occurs when blood flow slows, and has been strongly associated with thrombus formation and increased stroke risk, making it an important prognostic indicator. The underlying mechanism of LA SEC is thought to involve echogenic red blood cell aggregates formed due to low shear rates, but the roles of platelets and the coagulation cascade remain unclear.
View Article and Find Full Text PDF