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We examined the psychometric properties and criterion validity of the Sexual Minority Adolescent Stress Inventory (SMASI) among 730 sexual minority (SM) and transgender and gender-diverse (TGD) youth aged 14 to 24 years who participated in a human immunodeficiency virus study. We tested the factor structure of the global scale and subscales and measurement invariance across age, gender identity, sex assigned at birth, sexual identity, ethnoracial identity, and city. For criterion validity, we regressed mental health and substance use measures on the global scale. The global scale had excellent fit (comparative fit index = 0.95) and high reliability (omega = 0.89). Subscale model fit was adequate. We confirmed invariance by gender identity and age and established criterion validity. The SMASI exhibits strong psychometric properties among SM emerging adults and TGD youth. Modifications could enhance the SMASI to better capture both sexual and gender minority stress among ethnoracial minority youth.
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http://dx.doi.org/10.1089/lgbt.2023.0253 | DOI Listing |
JMIR Cancer
September 2025
Department of Health Outcomes and Biomedical Informatics, University of Florida, 1889 Museum Road, Suite 7000, Gainesville, FL, 32611, United States, 1 352 294-5969.
Background: Disparities in cancer burden between transgender and cisgender individuals remain an underexplored area of research.
Objective: This study aimed to examine the cumulative incidence and associated risk factors for cancer and precancerous conditions among transgender individuals compared with matched cisgender individuals.
Methods: We conducted a retrospective cohort study using patient-level electronic health record (EHR) data from the University of Florida Health Integrated Data Repository between 2012 and 2023.
J Med Internet Res
September 2025
Department of Psychological and Brain Sciences, Boston University, Boston, United States.
Background: Lesbian, gay, bisexual, transgender, queer/questioning, intersex, asexual (LGBTQIA+) researchers and participants frequently encounter hostility in virtual environments, particularly on social media platforms where public commentary on research advertisements can foster stigmatization. Despite a growing body of work on researcher virtual hostility, little empirical research has examined the actual content and emotional tone of public responses to LGBTQIA+-focused research recruitment.
Objective: This study aimed to analyze the thematic patterns and sentiment of social media comments directed at LGBTQIA+ research recruitment advertisements, in order to better understand how virtual stigma is communicated and how it may impact both researchers and potential participants.
Front Genet
August 2025
Center for Biomedical Ethics and Society, Vanderbilt University Medical Center, Nashville, TN, United States.
Research carried out by Vanderbilt University's and Medical Center's federally-funded transdisciplinary, highly interactive GetPreCiSe Center in Excellence for ELSI research on genomic privacy-involving over 40 scholars across computer and social sciences, law, and the humanities-is summarized by dividing the work into five categories: (1) the nature of risks posed by collection of genetic data; (2) legal and scientific methods of minimizing those risks; (3) methods of safely increasing the scope of genetic databases; (4) public perceptions of genetic privacy; and (5) cultural depictions of genetic privacy. While this research shows that the risk of unauthorized re-identification is often over-stated, it also identifies possible ways privacy can be compromised. Several technical and legal methods for reducing privacy risks are described, most of which focus not on collection of the data, but rather on regulating data security, access, and use once it is collected.
View Article and Find Full Text PDFPrev Med Rep
October 2025
Boston College, School of Social Work, 140 Commonwealth Avenue, Chestnut Hill, MA 02467, USA.
Objective: We aimed to examine the impact of cyberbullying and off-campus cyberbullying provisions in state anti-bullying laws on cyberbullying and whether the effects varied by sexual minority status.
Methods: Using data from the 2011-2021 Youth Risk Behavior Surveys (911,086 high school students in 44 states in the United States), we estimated difference-in-differences logistic regression models. Policies were categorized into three types: "strong" (including cyberbullying and off-campus provisions); "moderate" (cyberbullying provisions only); or "neither" (neither provision).