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http://dx.doi.org/10.1002/epd2.20245 | DOI Listing |
Macromol Biosci
September 2025
IMEM-BRT Group, Departament d'Enginyeria Química, EEBE, Universitat Politècnica de Catalunya, Barcelona, Spain.
This study investigates a multifunctional hydrogel system integrating carboxymethyl cellulose (CMC) in a 3D-printed limonene (LIM) scaffold coated with poly(3,4-ethylenedioxythiophene): polystyrene sulfonate (PEDOT:PSS). The system allows to enhance wound healing, prevent infections, and monitor the healing progress. CMC is crosslinked with citric acid (CA) to form the hydrogel matrix (CMC-CA), while the 3D-printed limonene (LIM) scaffold is embedded within the hydrogel to provide mechanical support.
View Article and Find Full Text PDFACS Nano
September 2025
Department of Electrical and Computer Engineering, Sungkyunkwan University, Suwon 16419, Republic of Korea.
Vagus nerve stimulation (VNS) is a promising therapy for neurological and inflammatory disorders across multiple organ systems. However, conventional rigid interfaces fail to accommodate dynamic mechanical environments, leading to mechanical mismatches, tissue irritation, and unstable long-term interfaces. Although soft neural interfaces address these limitations, maintaining mechanical durability and stable electrical performance remains challenging.
View Article and Find Full Text PDFPain Rep
October 2025
Physiology, Pharmacology and Neuroscience, School of Life Sciences, The University of Nottingham, Nottingham, United Kingdom.
Introduction: The dorsal horn (DH) of the spinal cord is physiologically immature at birth. Spinal excitability increases and wide dynamic range (WDR) neurons in lamina V have lowered activation thresholds and larger receptive field sizes.
Objective: The DH is composed of 5 laminae containing diverse interneuronal populations yet our understanding of the physiology of the DH is based on behavioural studies or extrapolation of single cell WDR recordings to the whole network.
Cureus
September 2025
Rheumatology, University Hospitals Coventry & Warwickshire, Coventry, GBR.
Complex regional pain syndrome (CRPS) is a debilitating chronic pain condition that may develop after fractures, surgery, or soft tissue trauma. It is characterized by pain disproportionate to the initial injury, often accompanied by sensory, motor, autonomic, and trophic changes. Despite extensive research, pathophysiology remains unclear, and treatment approaches are varied, with inconsistent supporting evidence.
View Article and Find Full Text PDFFront Med (Lausanne)
August 2025
Department of Acupuncture and Moxibustion, Jaseng Korean Medicine Hospital, Seoul, Republic of Korea.
Vertebral compression fractures (VCFs) cause severe pain and functional impairments. Conventional treatments, including medication and vertebral augmentation, have limited efficacy and safety. Electroacupuncture (EA), which combines acupuncture with electrical stimulation, is a promising but under-studied approach for VCF management.
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