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The silicon nitride (SiN) coating exhibits promising potential in oral applications due to its excellent osteogenic and antibacterial properties. However, a comprehensive investigation of SiN coatings in the context of dental implants is still lacking, especially regarding their corrosion resistance and in performance. In this study, SiN coatings were prepared on a titanium surface using the nonequilibrium magnetron sputtering method. A systematic comparison among the titanium group (Ti), SiN coating group (SiN-Ti), and sandblasted and acid-etched-treated titanium group (SLA-Ti) has been conducted in and in . The results showed that the SiN-Ti group had the best corrosion resistance and antibacterial properties, which were mainly attributed to the dense structure and chemical activity of Si-O and Si-N bonds on the surface. Furthermore, the SiN-Ti group exhibited superior cellular responses in and new bone regeneration and osseointegration in , respectively. In this sense, silicon nitride coating shows promising prospects in the field of dental implantology.
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http://dx.doi.org/10.1021/acsbiomaterials.4c00427 | DOI Listing |
Probiotics Antimicrob Proteins
September 2025
Department of Microbiology, Faculty of Medicine, Shahid Sadoughi University of Medical Sciences, Yazd, Iran.
Anaerobic bacteria cause a wide range of infections, varying from mild to severe, whether localized, implant-associated, or invasive, often leading to high morbidity and mortality. These infections are challenging to manage due to antimicrobial resistance against common antibiotics such as carbapenems and nitroimidazoles. The empirical use of antibiotics has contributed to the emergence of resistant organisms, making the identification and development of new antibiotics increasingly difficult.
View Article and Find Full Text PDFOdontology
September 2025
Department of Biology, SR.C., Islamic Azad University, Tehran, Iran.
Streptococcus mutans, a key cause of dental caries, is not treated by conventional toothpaste, brushing, flossing, or antiseptic mouthwashes. This necessitates the development of enriched toothpaste. Cyanobacteria-derived phycoerythrin (PE) has antioxidant and antibacterial properties.
View Article and Find Full Text PDFNaturwissenschaften
September 2025
Department of Biomedical Engineering, Sri Sivasubramaniya Nadar College of Engineering, Kalavakkam, 603110, Tamil Nadu, India.
Wounds with extensive tissue damage are highly susceptible for microbial infections delaying the process of wound healing. Currently, biomaterials with therapeutic molecules emerged as key players in wound repairing. This work developed a novel collagen-based hydrogel loaded with allicin and silver nanoparticles.
View Article and Find Full Text PDFMicrobiologyopen
October 2025
Department of Agronomy, National Taiwan University, Taipei, Taiwan.
Currently, there is an increasing use of whole-genome sequencing (WGS) studies to investigate the molecular taxonomy, metabolic properties, enzyme capabilities, and bioactive substances of lactic acid bacteria (LAB) species. In this study, the genome of strain Pediococcus pentosaceus BBS1 was sequenced using the Illumina HiSeq. 2500 platform to determine its classification, annotate its main features, and evaluate its safety characteristics.
View Article and Find Full Text PDFDalton Trans
September 2025
Faculty of Chemistry, Nicolaus Copernicus University in Toruń, Gagarina 7, 87-100 Toruń, Poland.
This study comprehensively analyses two new ruthenium(III) complexes, [RuCl(Nic)][(CH)NH]DMF, 1, and [RuCl(3-HPA)][3-HHPA](EtOH), 2, (where Nic = nicotinic acid (vitamin B3), 3-HPA = anion of a 3-hydroxypicolinic acid), as potential antimicrobial agents, highlighting their physicochemical properties, nanoparticle formation, and cytotoxic activity. The complexes were fully characterised by a single crystal X-ray diffraction technique, Fourier-transform infrared, energy-dispersive X-ray, and electron paramagnetic resonance spectroscopies. The synthesis of micro- and nanoparticles (NPs) of these complexes was performed using the liquid anti-solvent crystallisation method.
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