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Background: The traditional surgical procedures for upper lumbar disc herniation (ULDH) usually lead to frequent complications. We aim to investigate the clinical efficacy of the unilateral biportal endoscopy (UBE) technique in treating upper lumbar disc herniation (ULDH).
Methods: From January 2020 to December 2021, the clinical data of 28 patients with ULDH treated with the UBE technique were collected and analyzed for surgery time under UBE, postsurgical drainage, postsurgical hospital stay, and complications. The clinical efficacy was evaluated according to the modified MacNab score, Oswestry disability index (ODI), and visual analogue scale (VAS) of low back pain and lower limb pain before the surgery; one week, one month, and three months after the surgery; and at the last follow-up.
Results: All patients underwent the UBE surgery successfully. The surgery time under UBE for non-fusion cases was 47.50 ± 11.84 min (monosegment) and 75.00 ± 20.66 min (two segments), while that for fusion cases was 77.50 ± 21.02 min. The postsurgical drainage for non-fusion cases was 25.00 ± 13.94 mL (monosegment) and 38.00 ± 11.83 mL (two segments), while that for fusion cases was 71.25 ± 31.72 mL. The postsurgical hospital stay was 8.28 ± 4.22 days. The follow-up time was 15.82 ± 4.54 months. The VAS score for each time period after the surgery was significantly lower (P < 0.05), while the ODI was significantly higher than that before the surgery (P < 0.05). According to the modified MacNab scoring standard, the ratio of excellent to good was 96.43% at the last follow-up. Two patients experienced transient numbness and pain in their lower limbs and no activity disorder after the surgery, and they recovered after conservative treatment.
Conclusions: The clinical effect of UBE technique in treating ULDH was reliable. According to the needs of the disease, the interlaminar approach or paraspinal approach of the UBE technique was selected. This technique took into account the effect of treatment, achieved the purpose of minimal invasiveness, and did not require special instruments. Therefore, it has the potential for clinical application.
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http://dx.doi.org/10.1186/s12891-024-07339-8 | DOI Listing |
Biomed Eng Lett
September 2025
Department of Mechanical Engineering, Sejong University, 209, Neungdong-Ro, Gwangjin-gu, Seoul, 05006 Republic of Korea.
Cage subsidence is a common complication following transforaminal lumbar interbody fusion (TLIF) that can lead to poor clinical outcomes, including recurrent pain and segmental instability. Conventional TLIF cage designs often fail to distribute stress evenly, increasing the risk of endplate damage and subsequent subsidence. This study aims to evaluate the effect of a modified TLIF cage with upper and lower open windows (lattice structure) in reducing cage subsidence in patients with lumbar degenerative disc disease (LDDD).
View Article and Find Full Text PDFWorld Neurosurg
September 2025
Swedish Neuroscience Institute, Seattle, WA; Seattle Science Foundation, Seattle, WA.
Introduction: Lateral Lumbar Interbody Fusion (LLIF) is based on a less-invasive access corridor through the retroperitoneum and psoas muscle, though concerns persist over postoperative weakness and neuropathy on the surgical side. This study investigates if the trans-psoas LLIF approach is associated with long-term changes in psoas morphology, hip flexor (HF) weakness, and lower extremity dysesthesia.
Methods: The authors retrospectively reviewed all LLIF cases at a single institution from January 2016 to June 2024.
J Peripher Nerv Syst
September 2025
Mayo Clinic Department of Neurology, Rochester, Minnesota, USA.
Aim: To report a novel case of biopsy-proven, mass spectrometry-confirmed, wild-type transthyretin amyloidosis (ATTRwt) in nerve.
Methods: The patient was identified and evaluated in the peripheral nerve clinic. Our nerve laboratory's pathology database and the literature were searched for prior evidence of pathologically confirmed cases of ATTRwt.
Comput Methods Biomech Biomed Engin
September 2025
School of Physical Therapy and Graduate Institute of Rehabilitation Science, College of Medicine, Chang Gung University, Taoyuan, Taiwan.
This study compared biomechanical impacts of conventional open surgery (COS) and minimally invasive surgery (MIS) for spondylolisthesis using a musculoskeletal model with in-vivo data from 31 patients undergoing L4-L5 fusion. Pre- and post-operative conditions with simulated muscle injury were analyzed, focusing on kinematics, muscle forces, and adjacent segment loading. Both methods altered lumbosacral parameters, but COS caused greater lumbar-pelvic rhythm reduction (60% vs.
View Article and Find Full Text PDFBMC Musculoskelet Disord
September 2025
The Department of Spine Surgery, Tianjin Hospital, Tianjin University, 406 Jiefang Southern Road, Tianjin, China.
Background: Lumbar cartilage endplate (CEP) structures show low signal intensity on conventional magnetic resonance imaging (MRI), making them hard to observe and quantify. This often results in poor correlation between conventional MRI findings and low back pain (LBP) symptoms and provides inadequate guidance for clinical decisions.
Methods: The study included Twenty-five healthy volunteers and forty-one patients with LBP.