Category Ranking
98%
Total Visits
921
Avg Visit Duration
2 minutes
Citations
20
Article Abstract
Download full-text PDF |
Source |
|---|---|
| http://www.ncbi.nlm.nih.gov/pmc/articles/PMC11057628 | PMC |
| http://dx.doi.org/10.2147/NSS.S474037 | DOI Listing |
Publication Analysis
Top Keywords
Similar Publications
Circadian Rhythm Disruption and Sleep Disorders in Alzheimer's Disease: Mechanistic Insights and Therapeutic Potentials.
Neuro Endocrinol Lett
September 2025
Department of Biomedical and Life Sciences, Lancaster University, UK.
Alzheimer's Disease (AD) is the leading cause of dementia worldwide, with significant cognitive and behavioural impairments that devastate individuals and their families. Cohort-level findings, demonstrate the broader population-level implications of Sleep and Circadian Rhythm Disruption (SCRD) in AD and underscore the need for early interventions, emphasizing the importance of timely action. However, the mechanism remains unclear.
View Article and Find Full Text PDFSerotonergic receptor binding in the brainstem in the Sudden Infant Death Syndrome in a high-risk population.
PLoS One
September 2025
Department of Pathology, Boston Children's Hospital, Harvard School of Medicine, Boston, Massachusetts, United States of America.
The Sudden Infant Death Syndrome (SIDS) is a major global health problem, with increased risk among socioeconomically disadvantaged populations. We propose SIDS, or a subset, is due to a defect in the brainstem serotonin system mediating cardiorespiratory integration and arousal. This defect impinges on homeostasis during a critical developmental period in infancy, especially in populations experiencing maternal and infantile stress, resulting in sleep-related sudden death.
View Article and Find Full Text PDFScheduled feeding improves behavioral outcomes and reduces inflammation in a mouse model of fragile X syndrome.
Elife
September 2025
Department of Psychiatry & Biobehavioral Sciences, University of California, Los Angeles, Los Angeles, United States.
Fragile X syndrome (FXS), a leading inherited cause of intellectual disability and autism, is frequently accompanied by sleep and circadian rhythm disturbances. In this study, we comprehensively characterized these disruptions and evaluated the therapeutic potential of a circadian-based intervention in the fragile X mental retardation 1 () knockout (KO) mouse. The KO mice exhibited fragmented sleep, impaired locomotor rhythmicity, and attenuated behavioral responses to light, linked to an abnormal retinal innervation and reduction of light-evoked neuronal activation in the suprachiasmatic nucleus.
View Article and Find Full Text PDFRestless Eyes at Night: A Novel Variant of Restless Legs Syndrome.
Eur J Case Rep Intern Med
August 2025
Department of General Medicine, Chiba University Hospital, Chiba, Japan.
Introduction: Restless legs syndrome (RLS) is a common sensorimotor disorder that primarily affects the lower extremities. This condition is characterized by unpleasant sensations and an irresistible urge to move the affected body regions, typically during periods of rest or at night. While RLS most commonly involves the legs, atypical variants affecting other body parts, including the arms, abdomen, face, and even the head, have increasingly been reported.
View Article and Find Full Text PDFEvaluation of Joint Effect of Frailty and Sleep Health on Cardiometabolic Multimorbidity in Aging Population.
Nat Sci Sleep
September 2025
Department of Geriatrics, Tianjin Medical University General Hospital; Tianjin Key Laboratory of Elderly Health; Tianjin Geriatrics Institute, Tianjin, People's Republic of China.
Background: Sleep and frailty are established influencing factors for cardiometabolic diseases (CMDs). However, their joint effects on cardiometabolic multimorbidity (CMM) in older adults remain poorly understood. This study aimed to assess the joint effect of sleep health and frailty on CMD prevalence and severity, with an emphasis on subgroup-specific health risk profiles.
View Article and Find Full Text PDF