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Article Abstract
Noninflammatory nodules arising from the injection of biostimulatory fillers persist as an unwanted complication. Pathologically, noninflammatory nodules may arise from superficial injection, accidental boluses, or incorrect concentration of microparticles contained within the filler. This case report introduces a method for reversing calcium hydroxylapatite (CaHA) using focused mechanical vibration. An in situ hyperdilution was created by injecting saline into the nodule core to prepare it for resuspension. Topical microneedling was subsequently applied to generate vibrations, aiming to disperse the accumulated CaHA particles. The outcome demonstrated a significant reduction in the size and visibility of the nodule. This combined saline-microneedling approach offers a potential noninvasive, nonpharmacologic solution for managing superficial CaHA nodules.
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| http://www.ncbi.nlm.nih.gov/pmc/articles/PMC11033680 | PMC |
| http://dx.doi.org/10.1093/asjof/ojae018 | DOI Listing |
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Article Synopsis
- The study investigates the safety of a new hybrid filler, combining calcium hydroxylapatite (CaHA) and cohesive polydensified matrix-based hyaluronic acid (CPM-HA), which is gaining popularity in aesthetic medicine for its benefits in tissue elevation and reduced volume loss after injection.
- A total of 2112 patients were treated with these premixed fillers between March 2018 and December 2023, and only 5 minor adverse events (0.24%) were reported, indicating a strong safety profile.
- The findings align with previous research, reinforcing the idea that this hybrid filler blend is safe for use in aesthetic rejuvenation treatments.