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Due to the high suitability of semi-supervised learning for medical image segmentation, a plethora of valuable research has been conducted and has achieved noteworthy success in this field. However, many approaches tend to confine their focus to a singular semi-supervised framework, thereby overlooking the potential enhancements in segmentation performance offered by integrating several frameworks. In this paper, we propose a novel semi-supervised framework named Pesudo-Label Mean Teacher (PLMT), which synergizes the self-training pipeline with pseudo-labeling and consistency regularization techniques. In particular, we integrate the student-teacher structure with consistency loss into the self-training pipeline to facilitate a mutually beneficial enhancement between the two methods. This structure not only generates remarkably accurate pseudo-labels for the self-training pipeline but also furnishes additional pseudo-label supervision for the student-teacher framework. Moreover, to explore the impact of different semi-supervised losses on the segmentation performance of the PLMT framework, we introduce adaptive loss weights. The PLMT could dynamically adjust the weights of different semi-supervised losses during the training process. Extension experiments on three public datasets demonstrate that our framework achieves the best performance and outperforms the other five semi-supervised methods. The PLMT is an initial exploration of the framework that melds the self-training pipeline with consistency regularization and offers a comparatively innovative perspective in semi-supervised image segmentation.
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ArXiv
April 2025
Imaging Biomarkers and Computer-Aided Diagnosis Laboratory, Radiology and Imaging Sciences, Clinical Center, National Institutes of Health, Bethesda MD, USA.
Radiologists routinely perform the tedious task of lesion localization, classification, and size measurement in computed tomography (CT) studies. Universal lesion detection and tagging (ULDT) can simultaneously help alleviate the cumbersome nature of lesion measurement and enable tumor burden assessment. Previous ULDT approaches utilize the publicly available DeepLesion dataset, however it does not provide the full volumetric (3D) extent of lesions and also displays a severe class imbalance.
View Article and Find Full Text PDFArXiv
April 2025
Imaging Biomarkers and Computer-Aided Diagnosis Laboratory, Radiology and Imaging Sciences, Clinical Center, National Institutes of Health, Bethesda MD, USA.
Universal lesion detection and tagging (ULDT) in CT studies is critical for tumor burden assessment and tracking the progression of lesion status (growth/shrinkage) over time. However, a lack of fully annotated data hinders the development of effective ULDT approaches. Prior work used the DeepLesion dataset (4,427 patients, 10,594 studies, 32,120 CT slices, 32,735 lesions, 8 body part labels) for algorithmic development, but this dataset is not completely annotated and contains class imbalances.
View Article and Find Full Text PDFComput Methods Programs Biomed
April 2025
Digital Medical Research Center, School of Basic Medical Sciences, Fudan University, Shanghai, 200032, China; Shanghai Key Laboratory of Medical Imaging Computing and Computer Assisted Intervention, Fudan University, Shanghai, 200032, China. Electronic address:
Background And Objective: Pathology image classification is crucial in clinical cancer diagnosis and computer-aided diagnosis. Whole Slide Image (WSI) classification is often framed as a multiple instance learning (MIL) problem due to the high cost of detailed patch-level annotations. Existing MIL methods primarily focus on bag-level classification, often overlooking critical instance-level information, which results in suboptimal outcomes.
View Article and Find Full Text PDFJ Imaging
July 2024
Hospital São Lucas, Pontifícia Universidade Católica do Rio Grande do Sul, Porto Alegre 90610-000, Brazil.
Precise annotations for large medical image datasets can be time-consuming. Additionally, when dealing with volumetric regions of interest, it is typical to apply segmentation techniques on 2D slices, compromising important information for accurately segmenting 3D structures. This study presents a deep learning pipeline that simultaneously tackles both challenges.
View Article and Find Full Text PDFPLoS One
April 2024
Sergeant schools of Army Academy of Armored Forces, Changchun, Jilin, China.
Due to the high suitability of semi-supervised learning for medical image segmentation, a plethora of valuable research has been conducted and has achieved noteworthy success in this field. However, many approaches tend to confine their focus to a singular semi-supervised framework, thereby overlooking the potential enhancements in segmentation performance offered by integrating several frameworks. In this paper, we propose a novel semi-supervised framework named Pesudo-Label Mean Teacher (PLMT), which synergizes the self-training pipeline with pseudo-labeling and consistency regularization techniques.
View Article and Find Full Text PDF