Optimal surgical population for cervical lymph node dissection in PTC.

Front Oncol

Department of Pathology, Liaocheng People's Hospital, Affiliated to Shandong First Medical University, Liaocheng, Shandong, China.

Published: April 2024


Category Ranking

98%

Total Visits

921

Avg Visit Duration

2 minutes

Citations

20

Article Abstract

Objective: There is still controversy about whether cervical lymph node dissection should be performed in surgical treatment of PTC. Based on the data of thyroid cancer patients from Liaocheng People's Hospital from 2015 to 2018, this study focused on appropriate indications for cervical lymph node dissection surgery.

Methods: The clinical and pathological data of patients with initial treatment of PTC in thyroid surgery department from 2015 to 2018 were collected. In all cases, 1001 patients underwent total thyroidectomy + central lymph node dissection, and 1107 patients underwent total thyroidectomy + central + cervical lymph node dissection.

Results: The average metastasis rate of all cases was 57.23%, and even the metastasis rate of PTMC was as high as 48.97%. The total metastasis rate of central and lateral cervical lymph nodes was 74.44%, and the cervical lymph nodes were present in 49.32% of the metastatic cases. In 55.56% of the cases, the tumor diameter was more than 1 cm, and the metastasis rate of cervical lateral area was 56%. With the increase of tumor diameter, the cervical metastasis rate increased from 22.54% to 73.33%.

Conclusion: The metastasis rate of PTC is more than 50%, and nearly half of them have cervical metastasis, especially in patients with high risk factors. We observed that PTC 1 cm or greater has significant rates of metastasis.

Download full-text PDF

Source
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC11026636PMC
http://dx.doi.org/10.3389/fonc.2024.1280607DOI Listing

Publication Analysis

Top Keywords

cervical lymph
24
metastasis rate
24
lymph node
20
node dissection
16
cervical
9
treatment ptc
8
2015 2018
8
patients underwent
8
underwent total
8
total thyroidectomy
8

Similar Publications

Wiskott-Aldrich syndrome complicated with IgG4-related Sclerosing disease: A case report and literature review.

Allergol Immunopathol (Madr)

September 2025

Division of Immunology and Allergy, Department of Internal Medicine, Ankara University School of Medicine, Ankara, Türkiye.

Wiskott-Aldrich Syndrome (WAS) is an X-linked immunodeficiency characterized by eczema, microthrombocytopenia, and recurrent infections. Immunoglobulin G4-related disease (IgG4-RD) is a fibroinflammatory disorder involving various organs. We present a 34-year-old male with WAS who developed cervical lymphadenopathy and parotid gland swelling.

View Article and Find Full Text PDF

Clinical practice guidelines for esophagogastric junction cancer (EGJ GLs) were published in 2023. In order to evaluate how EGJ GLs have been adopted into clinical practice worldwide and to identify any outstanding clinical questions to be addressed in the next edition, this survey was conducted. An electronic questionnaire was developed.

View Article and Find Full Text PDF

Synchronous malignancies involving the oropharynx and thyroid gland are rare. We report the case of a 52-year-old female diagnosed with human papillomavirus (HPV)-associated oropharyngeal squamous cell carcinoma (OPSCC) with a concurrent, clinically occult papillary thyroid carcinoma (PTC). The patient initially presented with HPV-associated OPSCC and concerns for cervical lymphadenopathy, presumed to be linked to regional metastasis from the oropharyngeal primary.

View Article and Find Full Text PDF

This research aimed to investigate the preoperative risk factors for lymph node metastasis (LNM) in medullary thyroid carcinoma (MTC) using clinical, pathological, serological, ultrasound, and radiomics characteristics. Additionally, it aimed to explore the diagnostic precision of ultrasound (US) for MTC and LNM. A retrospective analysis of 111 nodules was eligible from 104 patients from January 1, 2000, to December 28, 2024.

View Article and Find Full Text PDF