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http://dx.doi.org/10.1183/13993003.00152-2024 | DOI Listing |
Zhonghua Jie He He Hu Xi Za Zhi
August 2025
Department of Respiratory and Critical Care Medicine, China-Japan Friendship Hospital, National Center for Respiratory Medicine, Institute of Respiratory Diseases, Chinese Academy of Medical Sciences, National Clinical Medical Research Center for Respiratory Diseases, Beijing 100029, China.
Respiratory infections have a high incidence rate globally. As an important biological specimen that is routinely monitored in the respiratory system, the physical properties of sputum can reflect the pathophysiological state of the respiratory system and are therefore significant in the diagnosis and prognosis of respiratory diseases. This article reviewed the research progress on bedside assessment of sputum, focusing on the assessment methods of three core dimensions: sputum color, viscosity, and volume.
View Article and Find Full Text PDFChronic Obstr Pulm Dis
July 2025
Pulmonology Department, Unidade Local de Saúde de Santo António, Porto, Portugal.
Purpose: Chronic Obstructive Pulmonary Disease (COPD) remains a challenging condition to manage due to its variability in clinical presentation and progression. While the disease control is a well-defined concept in asthma, its relevance in COPD is less clear. This study aimed to evaluate the clinical utility of COPD control framework, developed in Spain, in Portuguese outpatients by analyzing exacerbation rates among controlled and uncontrolled patients.
View Article and Find Full Text PDFMol Biotechnol
July 2025
Pediatric Infectious Diseases Research Center (PIDRC), Tehran University of Medical Sciences (TUMS), Tehran, Iran.
Acute Respiratory Infections (ARIs) are a leading cause of pediatric mortality, with Pseudomonas aeruginosa as a key pathogen. This study evaluated Recombinase Polymerase Amplification (RPA)-ELISA for rapid detection of P. aeruginosa in respiratory samples (n = 101).
View Article and Find Full Text PDFHeart Lung
June 2025
Health Technology & Services Research, TechMed Centre, University of Twente, Enschede, Netherlands; Department of Pulmonary Medicine, Medisch Spectrum Twente, Enschede, Netherlands; Clinical Research Center, Rijnstate Hospital, Arnhem, Netherlands. Electronic address:
Background: Chronic obstructive pulmonary disease (COPD) and chronic heart failure (CHF) commonly co-exist and share symptoms, which complicates disease management. It is unclear how COPD and CHF deterioration inter(re)act.
Objective: This study aimed to assess the interplay between COPD and CHF deterioration on group and individual level.
Biosensors (Basel)
May 2025
Multidisciplinary Sepsis Group, Health Research Institute of the Balearic Islands (IdISBa), 07120 Palma de Mallorca, Spain.
Patients with chronic obstructive pulmonary disease (COPD) often experience acute exacerbations characterized by elevated neutrophilic inflammation in the lungs. Currently, this condition is diagnosed through visual inspection of sputum color and volume, a method prone to personal bias and unsuitable for patients who are unable to expectorate spontaneously. In this manuscript, we present a novel approach for measuring and monitoring exhaled myeloperoxidase (MPO), a biomarker of neutrophilic airway inflammation, without the need for sputum analysis.
View Article and Find Full Text PDF