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Approximately 14% COVID-19 patients, develop acute hypoxic respiratory failure. A high flow nasal cannula device might be preferred to obtain an oxygen saturation above 90% in these cases. In resource limited settings, where high flow nasal cannula is not an option, additional low flow oxygen therapy through nasal prongs could be added to non-rebreathing mask with a reservoir bag. The possible mechanisms of the improved oxygenation could be: 1. improved oxygen-air mixing in large airways, 2. increased oxygen concentration inside the non-rebreathing mask, 3. decrease in rebreathing of carbon-dioxide from the non-rebreathing mask. This method of oxygen supplementation is easy to assemble, cost-effective and helpful in management of acute hypoxemic COVID-19 patients, whenever there is crisis of high flow nasal cannula machine. Its effectiveness needs to be assessed by a randomized controlled trial.
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http://dx.doi.org/10.1016/j.tacc.2021.02.004 | DOI Listing |
Front Allergy
August 2025
Department of Surgery, University of Auckland, Auckland, New Zealand.
Allergic rhinitis (AR) and chronic rhinosinusitis (CRS) are common respiratory conditions that significantly impact patient health and contribute to substantial healthcare burdens. While conventional treatments offer symptom relief, many patients continue to experience persistent symptoms, side effects, or resistance to standard therapies. This highlights the growing need for novel, non-invasive, and sustainable therapeutic strategies to manage chronic airway inflammation.
View Article and Find Full Text PDFEur J Intern Med
September 2025
Division of Respiratory Diseases with Intermediate Respiratory Intensive Care Units, Central Hospital of Bolzano, Bolzano, Italy.
Pediatr Pulmonol
September 2025
Intensive Care Service, Hospital Germans Trias i Pujol, Badalona, Spain.
Purpose: There is limited evidence to guide the use of enteral nutrition (EN) for children with bronchiolitis who received Humidified high flow nasal cannula (HHFNC) and often kept nil per mouth for aspiration and progression to mechanical ventilation risk.
Methods: This quality improvement project included children with bronchiolitis who were supported by HHFNC in the paediatric intensive care unit (PICU). An algorithm to increase EN use in those participants was created by stakeholders.
Medicine (Baltimore)
September 2025
Department of Chest Diseases, Health Ministry of the Turkish Republic, Bursa City Hospital, Bursa, Türkiye.
Using high-flow nasal cannula (HFNC) in patients with hypoxemic respiratory failure to avoid intubation raises concerns about its potential to increase mortality due to delayed intubation. Identifying at-risk patients is essential. While the literature predicts risk with oxygen-based indices (ROX, SpO2/FiO2, PaO2/FiO2), we aimed to detect ventilation insufficiency.
View Article and Find Full Text PDFBMC Res Notes
September 2025
Department of Anesthesiology, Aga Khan University and Hospital (AKUH), Karachi, Pakistan.