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The robotic drilling of assembly holes is a crucial process in aerospace manufacturing, in which measuring the normal of the workpiece surface is a key step to guide the robot to the correct pose and guarantee the perpendicularity of the hole axis. Multiple laser displacement sensors can be used to satisfy the portable and in-site measurement requirements, but there is still a lack of accurate analysis and layout design. In this paper, a simplified parametric method is proposed for multi-sensor normal measurement devices with a symmetrical layout, using three parameters: the sensor number, the laser beam slant angle, and the laser spot distribution radius. A normal measurement error distribution simulation method considering the random sensor errors is proposed. The measurement error distribution laws at different sensor numbers, the laser beam slant angle, and the laser spot distribution radius are revealed as a pyramid-like region. The influential factors on normal measurement accuracy, such as sensor accuracy, quantity and installation position, are analyzed by a simulation and verified experimentally on a five-axis precision machine tool. The results show that increasing the laser beam slant angle and laser spot distribution radius significantly reduces the normal measurement errors. With the laser beam slant angle ≥15° and the laser spot distribution radius ≥19 mm, the normal measurement error falls below 0.05°, ensuring normal accuracy in robotic drilling.
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http://dx.doi.org/10.3390/s24072059 | DOI Listing |
Fluids Barriers CNS
September 2025
Department of Medical Sciences, Neurology, Uppsala University, Uppsala, Sweden.
Background: Idiopathic normal pressure hydrocephalus (iNPH) predominantly manifests with gait disturbances, yet clinical assessments are vulnerable to confirmation bias, particularly post-shunt surgery. Blinded video evaluations are a method to enhance objectivity in gait assessment, but their reliability has never been systematically investigated. The aim was to evaluate the inter-rater reliability of blinded gait assessments in iNPH patients and to investigate how these assessments correlate with the Hellström iNPH scale and patient-reported health status following shunt surgery.
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September 2025
Department of Ophthalmology, Institute of Medicine, Tribhuvan University, B.P Koirala Lions Centre For Ophthalmic Studies, Kathmandu, Nepal.
Background: To evaluate the ganglion cell complex thickness in patients taking oral hydroxychloroquine.
Methods: In this hospital-based, cross-sectional, non-interventional, comparative study, 87 eyes of 87 patients taking hydroxychloroquine were recruited. All the patients underwent complete ophthalmological evaluation along with dilated fundus examination.
BMC Public Health
September 2025
Department of Social and Health Sciences in Sport, Bayreuth Center of Sport Science, University of Bayreuth, Bayreuth, Germany.
Background: Sedentary behavior (SB) and the absence of physical activity (PA) have become increasingly prevalent in modern societies due to changes in physical and social-environmental conditions, particularly in university students. This cross-sectional study aimed to describe and identify the prevalence and correlates of self-reported and accelerometer-determined SB and PA of German university students.
Methods: A convenience sample of 532 students participated in a questionnaire survey during the lecture period in the summer term 2018.
Cardiovasc Intervent Radiol
September 2025
Department of Radiology, Seoul National University College of Medicine, Seoul National University Bundang Hospital, 82, Gumi-ro 173Beon-gil, Bundang-gu, Seongnam-si, Gyeonggi-do, Republic of Korea.
Purpose: To evaluate the preclinical efficacy and safety of transarterial chemoembolization (TACE) using doxorubicin-loaded biocompatible cellulose nanoparticles in a rabbit VX2 liver tumor model.
Materials And Methods: Following institutional animal care committee approval, 23 rabbits with VX2 liver tumors were randomized into three groups: Group A (n = 9) received doxorubicin-loaded cellulose nanoparticles with ethiodized oil; Group B (n = 9) received doxorubicin with ethiodized oil; and Group C (n = 5) served as untreated controls. Tumor size was monitored via ultrasound for 4 weeks, and serum liver enzymes (aspartate transaminase and alanine transaminase) were measured on days 1, 3, and 7 to assess hepatotoxicity.
Nat Commun
September 2025
State Key Laboratory of Earth Surface Processes and Resource Ecology, Faculty of Geographical Science, Beijing Normal University, Beijing, 100875, China.
Rising atmospheric vapor pressure deficit (VPD)-a measure of atmospheric dryness, defined as the difference between saturated vapor pressure (SVP) and actual vapor pressure (AVP)-has been linked to increasing daily mean near-surface air temperatures since the 1980s. However, it remains unclear whether the faster increases in daily maximum temperature (T) relative to daily minimum temperature (T) have contributed to rising VPD. Here, we show that the faster rise in T compared with T over land has intensified VPD from 1980 to 2023.
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