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Objective: The objective of this study is to determine the validity and reliability of the red filter meibography by smartphone compared with infrared in assessing meibomian gland drop-out.
Methods And Analysis: An analytical cross-sectional study was done with a total of 35 subjects (68 eyes) with suspected MGD based on symptoms and lid morphological abnormalities. Meibomian glands were photographed using two smartphones (Samsung S9 and iPhone XR) on a slit-lamp with added red filter. Images were assessed subjectively using meiboscore by the two raters and drop-out percentages were assessed by ImageJ.
Results: There was no agreement in meiboscore and a minimal level of agreement in drop-out percentages between red filter meibography and infrared. Inter-rater reliability showed no agreement between two raters. Intra-rater reliability demonstrated weak agreement in rater 1 and no agreement in rater 2.
Conclusion: Validity of the red filter meibography technique by smartphones is not yet satisfactory in evaluating drop-out. Further improvement on qualities of images must be done and research on subjective assessment was deemed necessary due to poor results of intrarater and inter-rater reliability.
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http://dx.doi.org/10.1136/bmjophth-2023-001266 | DOI Listing |
Clin Pharmacol
September 2025
Department of Pharmacology and Clinical Pharmacy, Faculty of Pharmacy, Universitas Padjadjaran, Sumedang, Indonesia.
Red yeast rice (RYR) is an Asian indigenous medicine that ferments grains using the Monascus fungi, specifically . Monacolins, pigments, phenols, sterols, and benzopyrans, such as the mycotoxin citrinin, were proven to be present in RYR, contributing to its numerous effects. This study aims to provide a thorough overview of the in vitro and in vivo pharmacological activities of red yeast rice, its studies in humans, and a summary of recent case reports.
View Article and Find Full Text PDFAppl Environ Microbiol
September 2025
Department of Microbiology, Faculty of Science, University of Manitoba, Winnipeg, Manitoba, Canada.
Unlabelled: Although wastewater treatment plants harbor many pathogens, traditional methods that monitor the microbial quality of surface water and wastewater have not changed since the early 1900s and often disregard the presence of other types of significant waterborne pathogens such as viruses. We used metagenomics and quantitative PCR to assess the taxonomy, functional profiling, and seasonal patterns of DNA and RNA viruses, including the virome distribution in aquatic environments receiving wastewater discharges. Environmental water samples were collected at 11 locations in Winnipeg, Manitoba, along the Red and Assiniboine rivers during the Spring, Summer, and Fall 2021.
View Article and Find Full Text PDFAnal Chim Acta
November 2025
Key Laboratory of Analytical Science and Technology of Hebei Province, College of Chemistry and Materials Science, Hebei University, Baoding, 071002, PR China; Engineering Research Center of Ecological Safety and Conservation in Beijing-Tianjin-Hebei (Xiong'an New Area) of Ministry of Education, Bao
Background: In the contemporary era of rapid digital advancement, information security is closely associated with our daily life. From personal information to state secrets, all domains are intricately linked with information. Consequently, the significance of information security has garnered growing attention from an ever-increasing number of individuals.
View Article and Find Full Text PDFMol Genet Genomics
September 2025
Institute of Genetics, Vetsuisse Faculty, University of Bern, 3012, Bern, Switzerland.
The aim of this study was to investigate three unrelated Simmental calves with atypical white coat color, identify potential genetic causes using a trio-based whole-genome sequencing approach, and assess the prevalence of the identified variants in the breed. Several inherited alleles affecting coat color, ranging from fawn to red spotted and white-headed, have been described in Simmental cattle originating from Switzerland. However, no genetic variant has yet been associated with an almost completely white coat in this breed.
View Article and Find Full Text PDFJ Colloid Interface Sci
August 2025
School of Life Science, Xinghuacun College, Shanxi University, Taiyuan 030006, PR China. Electronic address:
Contamination by Bacillus anthracis in food and the environment poses a significant public health risk to both humans and animals, with dipicolinic acid (DPA) serving as an effective biomarker for its detection. In this work, a novel AI-assisted near-infrared ratiometric fluorescent sensing system based on rapid coordination cross-linking and multiple fluorescence response mechanisms was proposed for ultrafast and portable visual detection of Bacillus anthracis biomarkers. A near-infrared (NIR) ratiometric fluorescent probe with multiple fluorescence response mechanisms was developed for sensitive detection of DPA, using carbon dots (B-CDs) and CdTe quantum dots (QD686).
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