Category Ranking

98%

Total Visits

921

Avg Visit Duration

2 minutes

Citations

20

Article Abstract

Background: The diagnosis and management of cardiomyopathies (CMs) are subject to regional variations but no study to date has systematically evaluated the clinical pathways of patients with CMs. Aims: We aimed to assess the management pathway of CM patients in Poland. Methods: This population-based cross-sectional study was conducted based on data from 2016 to 2021 obtained from the national healthcare provider using ICD10 codes to identify CM patients. The treatment pathways of CM patients, defined as the sequence of visits to the public healthcare system and categorized as urgent hospitalization (UH) for disease exacerbation, elective hospitalization (EH), tertiary outpatient medical care (TMC), primary outpatient healthcare (general practice [GP]) were analyzed. Results: Between 2016 and 2021, 65 383 CM patients were analyzed (mean age: 60 years, 65.4% men). Total healthcare services provided to these patients involved hospitalization (47.2%), TMC (16.5%), and GP (27.5%). The first registration CM diagnosis was made on an inpatient basis in 93.4% of patients (UH: 68.1%; EH: 25.1%). The mortality rate during the analyzed period was 39.8% for the total CM population, 43.9% for patients who were registered in the system only once (47% of all subjects), and 65.4% for patients with a Charlson Comorbidity Index ≥ 5. Conclusions: The diagnosis of CMs in Poland is established very late mainly during hospitalization for exacerbation of the disease. This may have an impact on the poor prognosis of CM patients especially those with a high comorbidity burden. This study highlights the urgent need for improvement in CM management in Poland.

Download full-text PDF

Source
http://dx.doi.org/10.33963/v.phj.100178DOI Listing

Publication Analysis

Top Keywords

patients
11
treatment pathways
8
defined sequence
8
sequence visits
8
visits public
8
pathways patients
8
2016 2021
8
pathways defined
4
public health
4
health system
4

Similar Publications

Spinal muscular atrophy (SMA) is a neuromuscular disease caused by low levels of SMN protein. Several therapeutic approaches boosting SMN are approved for human patients, delivering remarkable improvements in lifespan and symptoms. However, emerging phenotypes, including neurodevelopmental comorbidities, are being reported in some treated SMA patients, indicative of alterations in brain development.

View Article and Find Full Text PDF

Background: Active vitamin D metabolites, including 25-hydroxyvitamin D (25D) and 1,25-dihydroxyvitamin D (1,25D), have potent immunomodulatory effects that attenuate acute kidney injury (AKI) in animal models.

Methods: We conducted a phase 2, randomized, double-blind, multiple-dose, 3-arm clinical trial comparing oral calcifediol (25D), calcitriol (1,25D), and placebo among 150 critically ill adult patients at high-risk of moderate-to-severe AKI. The primary endpoint was a hierarchical composite of death, kidney replacement therapy (KRT), and kidney injury (baseline-adjusted mean change in serum creatinine), each assessed within 7 days following enrollment using a rank-based procedure.

View Article and Find Full Text PDF

Background: Experience with icodextrin use in children on long-term peritoneal dialysis is limited. We describe international icodextrin prescription practices and their impact on clinical outcomes: ultrafiltration, blood pressure control, residual kidney function (RKF), technique and patient survival.

Methods: We included patients under 21 years enrolled in the International Pediatric Peritoneal Dialysis Network (IPPN) between 2007 and 2024, on automated PD with a daytime dwell.

View Article and Find Full Text PDF

Complexity and Health Care Utilization in Infant ESKD.

Kidney360

September 2025

Department of Pediatrics, Division of Pediatric Nephrology, Baylor College of Medicine, Houston, TX, United States.

Background: Dialysis in neonates with ESKD is often associated with multiple comorbidities and the need for more intensified dialysis regimens. With recent advances in prenatal interventions and infant specific KRT, survival of neonates with ESKD has improved over the last decade. Little is known however about the impact on the health care system of improved survival in this population.

View Article and Find Full Text PDF

Role of Systemic Glucocorticoids in Reducing IgA and Galactose-Deficient IgA1 Levels in IgA Nephropathy.

Clin J Am Soc Nephrol

September 2025

Kidney Division, Peking University First Hospital, Peking University Institute of Nephrology; Key Laboratory of Kidney Disease, Ministry of Health of China; Key Laboratory of Chronic Kidney Disease Prevention and Treatment (Peking University), Ministry of Education, China.

Background: The Therapeutic Effects of Steroids in IgA Nephropathy Global (TESTING) trial demonstrated that glucocorticoid therapy reduced proteinuria and improved kidney outcomes in patients with Immunoglobulin A Nephropathy (IgAN). Galactose-deficient IgA1 (Gd-IgA1) plays a central role in IgAN pathogenesis by promoting immune complex formation. However, the effects of glucocorticoid on pathogenic IgA levels remain unclear.

View Article and Find Full Text PDF