Category Ranking
98%
Total Visits
921
Avg Visit Duration
2 minutes
Citations
20
Article Abstract
Background: Tumoral calcinosis is a condition characterized by deposits of calcium phosphate crystals in extra-articular soft tissues, occurring in hemodialysis patients. Calcium phosphate crystals are mainly composed of hydroxyapatite, which is highly infiltrative to tissues, thus making complete resection difficult. An adjuvant method to remove or resolve the residual crystals during the operation is necessary.
Case Summary: A bicarbonate Ringer's solution with bicarbonate ions (28 mEq/L) was used as the adjuvant. After resecting calcium phosphate deposits of tumoral calcinosis as much as possible, while filling with the solution, residual calcium phosphate deposits at the pseudocyst wall can be gently scraped by fingers or gauze in the operative field. A 49-year-old female undergoing hemodialysis for 15 years had swelling with calcium deposition for 2 years in the shoulders, bilateral hip joints, and the right foot. A shoulder lesion was resected, but the calcification remained and early re-deposition was observed. Considering the difficulty of a complete rection, we devised a bicarbonate dissolution method and excised the foot lesion. After resection of the calcified material, the residual calcified material was washed away with bicarbonate Ringer's solution.
Conclusion: The bicarbonate dissolution method is a new, simple, and effective treatment for tumoral calcinosis in hemodialysis patients.
Download full-text PDF |
Source |
|---|---|
| http://www.ncbi.nlm.nih.gov/pmc/articles/PMC10999962 | PMC |
| http://dx.doi.org/10.5312/wjo.v15.i3.302 | DOI Listing |
Publication Analysis
Top Keywords
Similar Publications
Idiopathic Scrotal Calcinosis: Sonographic Hallmarks.
Ultrasound Q
December 2025
Department of Radiology, Mayo Clinic, Jacksonville, FL.
Idiopathic scrotal calcinosis (ISC) is a rare, benign dermatological condition consisting of deposits of calcium within the scrotal skin. On examination, ISC is characterized by painless, firm nodules and papules localized to the scrotal skin. Typically presenting in adolescence or early adulthood, ISC is more prevalent in males aged 20 to 40, though cases have been reported across all age groups.
View Article and Find Full Text PDFBreast cancer classification based on the integration of diagnostic algorithms for calcifications and masses using a mixture of experts.
PLoS One
September 2025
Department of Diagnostic Imaging, Tohoku University Graduate School of Medicine, 2-1 Seiryo-Machi, Aoba-ku, Sendai, Miyagi, Japan.
Purpose: To investigate the effectiveness of an integrated deep-learning (DL) algorithm, the Mixture of Radiological Findings Specific Experts (MoRFSE), in breast cancer classification by imitating the diagnostic decision-making process of radiologists.
Methods: A total of 2,764 mammographic images (1,462 breast cancer, 248 benign lesions, and 1,054 normal breast tissue) from the TOMPEI-CMMD were used. The MoRFSE comprises three DL models: a gate network for categorization (gNet) and two classification expert networks (cExp and mExp) specialized in capturing the distinct characteristics of calcifications and masses, respectively.
Recent Advances in Deciphering Normal and Diseased Aortic Valve Biology Using Transcriptomic Technologies.
J Cell Mol Med
September 2025
Institute of Cellular Biology and Pathology "Nicolae Simionescu", Bucharest, Romania.
Calcific aortic valve disease (CAVD) is a growing global health burden, with no approved pharmacological treatments to date, indicating a substantial therapeutic gap and the need for deeper insight into its underlying mechanisms. Transcriptomic approaches, particularly RNA sequencing (RNAseq) and single-cell sequencing (scRNAseq), are emerging as powerful tools for unravelling the complex biology of the aortic valve (AV) in both normal and diseased states. This review summarises recent advances in our understanding of AV structure and function, with emphasis on valvular cell plasticity, heterogeneity and intercellular interactions-especially between valvular endothelial cells (VECs) and monocytes under physiological and pathological conditions.
View Article and Find Full Text PDFMultiquadrant presentation of eruption sequestrum: a case report and literature review.
BMC Oral Health
September 2025
Xiangya Stomatological Hospital and Xiangya School of Stomatology, Hunan Key Laboratory of Oral Health Research, Hunan Clinical Research Center of Oral Major Diseases and Oral Health, Academician Workstation for Oral-maxilofacial and Regenerative Medicine, Central South University, Changsha, 410008,
Background: Eruption sequestrum (ES) is an uncommon condition characterized by irregular calcified tissues on the occlusal surfaces of erupting permanent molars, primarily in children. Despite its rarity, ES has been linked to potential complications, including gingivitis, occlusal trauma, and delayed tooth eruption.
Case Presentation: This paper reports a multiquadrant ES case affecting the first molars of bilateral maxillary and mandibular arches in a 6-year-old pediatric patient.
Automated quantification of abdominal aortic calcification using 3D nnU-Net: a novel approach to assess AAA rupture risk.
BMC Med Imaging
September 2025
Division of Vascular and Interventional Radiology, Department of General Surgery, Nanfang Hospital, Southern Medical University, Guangzhou, Guangdong Province, 510515, China.
Background: Abdominal aortic aneurysms (AAA) pose a serious rupture risk, heightened by aortic calcification. Traditional calcification scoring methods are slow and require expertise. This study aims to construct a convolutional neural network (nnU-Net) model for automatic quantification and segmentation of abdominal aortic calcification from a single CTA scan.
View Article and Find Full Text PDF