Category Ranking
98%
Total Visits
921
Avg Visit Duration
2 minutes
Citations
20
Article Abstract
In this study, the fermentation characteristics and functional properties of lactic acid bacteria-malted vinegar (LAB-MV) were investigated during the fermentation period. Changes in the components (organic acids, free sugars, free amino acids, β-glucan, and gamma-aminobutyric acid (GABA)) of MV (BWAF0d, BWAF10d, BWAF20d) and LAB-MV (LBWAF0d, LBWAF10d, LBWAF20d) were analyzed according to the fermentation time. The amounts of β-glucan and GABA in LBWAF20d were greater than those in BWAF20d (122.00 μg/mL, 83.06 μg/mL and 531.00 μg/mL, 181.31 μg/mL, respectively). The ACE1 and HMG-CoA reductase inhibitory activities of LBWAF20d were 98.16% (1/20 dilution factor, DF) and 91.01% (1/25 DF), respectively. The lipid accumulation ratio and total cholesterol levels in HepG2 cells treated with LBWAF20d (1/200 DF) were reduced by 45.85% and 54.48%, respectively, compared to those in the untreated group. These results suggest that LAB-MV, which comprises barley wine manufactured from LAB and yeast, may improve hepatic lipid metabolism.
Download full-text PDF |
Source |
|---|---|
| http://www.ncbi.nlm.nih.gov/pmc/articles/PMC10992063 | PMC |
| http://dx.doi.org/10.1007/s10068-024-01528-w | DOI Listing |
Publication Analysis
Top Keywords
Similar Publications
Genomic Characterisation of Limosilactobacillus fermentum CRL2085 Unveiling Probiotic Traits for Application in Cattle Feed.
Environ Microbiol Rep
October 2025
Reference Center for Lactobacilli (CERELA-CONICET), San Miguel de Tucumán, Argentina.
Limosilactobacillus fermentum CRL2085, isolated from feedlot cattle rations, displayed high efficiency as a probiotic when administered to animals. A comprehensive genomic analysis was performed to elucidate the genetic basis underlying its probiotic potential. Fifteen genomic islands and CRISPR-Cas elements were identified in its genome.
View Article and Find Full Text PDFA SERS-active microneedle array for rapid and minimally invasive lactic acid detection.
Anal Chim Acta
November 2025
State Key Laboratory of Digital Medical Engineering, School of Biological Science and Medical Engineering, Southeast University, Nanjing, 210096, China. Electronic address:
Background: During intense exercise, anaerobic metabolism predominantly produces energy in the body, resulting in lactic acid (LA) accumulation, which contributes to muscle fatigue and soreness and may also impair neurological and cardiovascular functions. In endurance sports, the lactate threshold (LT) is a key indicator of an athlete's capacity to clear and utilize LA, directly influencing athletic performance and endurance. Therefore, LA detection is crucial for assessing the physical condition of both athletes and the general population, as well as for optimizing training programs.
View Article and Find Full Text PDFA novel treatment for diabetic nephropathy: Folate receptor-targeted delivery of TLR4 siRNA via functionalized PLGA nanoparticles in streptozotocin-induced diabetic murine models.
Nanomedicine
September 2025
The Second Hospital & Clinical Medical School, Lanzhou University, Lanzhou, 730000, Gansu, People's Republic of China; Department of Nephrology, The Second Hospital & Clinical Medical School, Lanzhou University, Lanzhou, 730030, Gansu, People's Republic of China; Key laboratory of nephropathy, The S
Diabetic kidney disease (DKD), a prominent microvascular complication of diabetes mellitus and the leading cause of end-stage renal disease (ESRD), was addressed through a novel nanotherapeutic approach. This study engineered folic acid-conjugated poly(lactic-co-glycolic acid) nanoparticles (FA-PLGA NPs) for the folate receptor (FR)-targeted delivery of Toll-like receptor 4 small interfering RNA (TLR4 siRNA) to treat diabetic nephropathy (DN). In a streptozotocin-induced DN murine model, administration of FA-PLGA NPs/TLR4 siRNA significantly mitigated renal injury compared to untreated DN controls.
View Article and Find Full Text PDFThe effect of sonicated cell-free supernatant from Lacticaseibacillus paracasei B1 and Lactiplantibacillusplantarum O24 on selected quality determinants of cooked pork sausages.
Meat Sci
September 2025
Department of Food Gastronomy and Food Hygiene, Institute of Human Nutrition Sciences, Warsaw University of Life Sciences (SGGW), Nowoursynowska 159C St., (Building No. 32), 02-776 Warsaw, Poland. Electronic address:
The aim of the study was to assess the effect of lyophilized cell-free supernatant (CFS) obtained from Lacticaseibacillus paracasei B1 and Lactiplantibacillus plantarum O24 cultures on the characteristics of cooked pork sausages stored by 21 days at 4 °C. The following parameters were assessed: antioxidant activity (ABTS, Reducing Power, Fe-chelating activity), texture parameters (hardness, springiness, gumminess, chewiness) and color changes (L*,a*,b*), as well as the fatty acid profile and TBARS content as an indicator of lipid oxidation. Microbiological status was also assessed.
View Article and Find Full Text PDFMapping between chain configuration and mechanical properties of poly(L-lactic acid) monofilaments via hydrolysis induction.
J Mech Behav Biomed Mater
August 2025
School of Mechanical Engineering, Jiangsu Key Laboratory for Design and Manufacturing of Precision Medicine Equipment, Southeast University, Nanjing, 211189, China. Electronic address:
Poly(L-lactic acid) (PLLA), as a substrate material, has been widely utilized in the field of biodegradable vascular stents. Prior to implantation, it is particularly crucial for these devices to assess the relationship of the mechanical properties and microstructures during full degradation cycle. Although previous studies have primarily focused on structural parameters such as crystallinity and molecular weight, there are relatively few reports that explore the impact of microstructure on mechanical performance from the perspective of chain configuration during the degradation.
View Article and Find Full Text PDF