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is the pragmatic skill of signallers who adjust the modality of their communicative signals to their recipient's attention state. This study provides the first comprehensive evidence for its onset and development in 7-to 20-month-olds human infants, and underlines its significance for language acquisition and evolutionary history. Mother-infant dyads ( = 30) were studied in naturalistic settings, sampled according to three developmental periods (in months); [7-10], [11-14], and [15-20]. Infant's signals were classified by dominant perceptible sensory modality and proportions compared according to their mother's , and . Maternal visual attention and infant-directed speech were influential on the onset and steepness of infants' communicative adjustments. The ability to inhibit silent-visual signals towards visually inattentive mothers ( adjustment) predated the ability to deploy audible-or-contact signals in this case ( adjustment). Maternal scaffolding of infant's early pragmatic skills through her infant-directed speech operates on the facilitation of infant's adjustment, the preference for oral over gestural signals, and the audio-visual combinations of signals. Additionally, breakdowns in maternal visual attention are associated with increased use of the audible-oral modality/channel. The evolutionary role of the sharing of attentional resources between parents and infants into the emergence of modern language is discussed.
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http://dx.doi.org/10.3389/fpsyg.2024.1257324 | DOI Listing |
JAMA Netw Open
September 2025
Social and Behavioral Sciences Branch, Division of Population Health Research, Eunice Kennedy Shriver National Institute of Child Health and Human Development, Bethesda, Maryland.
Importance: Higher intellectual abilities have been associated with lower mortality risk in several longitudinal cohort studies. However, these studies did not fully account for early life contextual factors or test whether the beneficial associations between higher neurocognitive functioning and mortality extend to children exposed to early adversity.
Objective: To explore how the associations of child neurocognition with mortality changed according to the patterns of adversity children experienced.
Nat Aging
September 2025
Aging Biomarker Consortium (ABC), Beijing, China.
The global surge in the population of people 60 years and older, including that in China, challenges healthcare systems with rising age-related diseases. To address this demographic change, the Aging Biomarker Consortium (ABC) has launched the X-Age Project to develop a comprehensive aging evaluation system tailored to the Chinese population. Our goal is to identify robust biomarkers and construct composite aging clocks that capture biological age, defined as an individual's physiological and molecular state, across diverse Chinese cohorts.
View Article and Find Full Text PDFFront Neurosci
August 2025
Department of First Clinical Medical College, Shandong University of Traditional Chinese Medicine, Jinan, China.
Background: Depression is a common mental disorder, and its diagnosis is highly dependent on subjective assessment. Electroencephalogram (EEG), as a non-invasive and economical neurophysiological tool, has garnered considerable attention in recent years in the research of auxiliary diagnosis and clinical application. However, there exists a limited number of articles that summarize this body of research.
View Article and Find Full Text PDFACS Omega
September 2025
Chongqing Key Laboratory of Green Synthesis and Applications, College of Chemistry, Chongqing Normal University, Chongqing 401331, China.
Nanozymes, which possess inherent catalytic properties that are akin to those of natural enzymes, have emerged as promising candidates for biomedical innovation. In this work, we successfully synthesize a Co Cu S nanoflower by the solvothermal and soaking method. Fortunately, through cobalt doping and microstructure design, its morphological structure and active sites have been optimized and adjusted, thus bestowing the Co Cu S nanoflower enhanced peroxidase-mimetic activity.
View Article and Find Full Text PDFFront Neurol
August 2025
Department of Radiology, Dongchangfu District People's Hospital, Liaocheng, Shandong, China.
Background: Understanding the neurological complications associated with diabetes mellitus is essential for developing comprehensive treatment strategies. Functional magnetic resonance imaging (fMRI) is a powerful tool for investigating brain functional and structural changes associated with various conditions, including diabetes mellitus.
Objectives: To analyze the application trends, research hotspots, and emerging frontiers of fMRI in diabetes mellitus research through a comprehensive bibliometric analysis.