Category Ranking
98%
Total Visits
921
Avg Visit Duration
2 minutes
Citations
20
Article Abstract
Purpose: To investigate sectoral differences in the relationship between intraocular pressure (IOP) dynamics during dark-room prone testing (DRPT) and visual field (VF) defect progression in primary open-angle glaucoma (POAG) patients.
Design: Retrospective, longitudinal study.
Participants: This retrospective study included 116 eyes of 84 POAG patients who underwent DRPT and had at least 5 reliable VF tests conducted over a more than 2-year follow-up period. We excluded eyes with mean deviation worse than -20 dB or a history of intraocular surgery or laser treatment.
Methods: Average total deviation (TD) was calculated in the superior, central, and inferior sectors of the Humphrey 24-2 or 30-2 program. During DRPT, IOP was measured in the sitting position, and after 60 minutes in the prone position in a dark room, IOP was measured again. The relationship between IOP change during DRPT, IOP after DRPT, and TD slope in each quadrant was analyzed with a linear mixed-effects model, adjusting for other potential confounding factors.
Main Outcome Measures: Total deviation slope in each quadrant, IOP change during DRPT, and IOP after DRPT.
Results: Intraocular pressure after DRPT and IOP change during DRPT were 18.16 ± 3.42 mmHg and 4.92 ± 3.12 mmHg, respectively. Superior TD slope was significantly associated with both IOP after DRPT (β = -0.28, P = 0.003) and IOP change during DRPT (β = -0.21, P = 0.029), while central (β = -0.05, P = 0.595; β = -0.05; P = 0.622) and inferior (β = 0.05, P = 0.611; β = 0.01, P = 0.938) TD slopes were not.
Conclusion: Dark-room prone testing might be a useful test to predict the risk of superior VF defect progression in eyes with POAG.
Financial Disclosure(s): The author(s) have no proprietary or commercial interest in any materials discussed in this article.
Download full-text PDF |
Source |
|---|---|
| http://dx.doi.org/10.1016/j.ogla.2024.03.007 | DOI Listing |
Publication Analysis
Top Keywords
Similar Publications
Sector-specific Association of Intraocular Pressure Dynamics in Dark-room Prone Testing and Visual Field Defect Progression in Glaucoma.
Ophthalmol Glaucoma
July 2024
Department of Ophthalmology, Tohoku University Graduate School of Medicine, Miyagi, Japan; Department of Ophthalmic Imaging and Information Analytics, Tohoku University Graduate School of Medicine, Miyagi, Japan; Department of Retinal Disease Control, Tohoku University Graduate School of Medicine, M
Purpose: To investigate sectoral differences in the relationship between intraocular pressure (IOP) dynamics during dark-room prone testing (DRPT) and visual field (VF) defect progression in primary open-angle glaucoma (POAG) patients.
Design: Retrospective, longitudinal study.
Participants: This retrospective study included 116 eyes of 84 POAG patients who underwent DRPT and had at least 5 reliable VF tests conducted over a more than 2-year follow-up period.
The association between intraocular pressure dynamics during dark-room prone testing and intraocular pressure over a relatively long-term follow-up period in primary open-glaucoma patients.
Graefes Arch Clin Exp Ophthalmol
March 2024
Department of Ophthalmology, Tohoku University Graduate School of Medicine, Miyagi, Japan.
Article Synopsis
- - The study aimed to explore how changes in intraocular pressure (IOP) during Dark-Room Prone Testing (DRPT) relate to IOP levels over a two-year period in patients with primary open-angle glaucoma.
- - A total of 84 eyes from 51 patients were analyzed, focusing on IOP measurements taken both in a sitting position and after lying prone in a dark room, with a focus on IOP fluctuations and maximum values.
- - Results showed a significant increase in IOP after DRPT, suggesting that short-term IOP responses can help predict long-term IOP changes in glaucoma patients.
Effect of combined water drinking test and dark room provocative testing in Caucasian eyes with narrow angles.
Eye (Lond)
January 2022
Maastricht University Medical Center, Maastricht, the Netherlands.
Purpose: To assess the usefulness of water drinking test and dark room provocative testing (WDT + DRPT) in current clinical practice by evaluating input parameters from Swept-source Optical Coherence Tomography (SS-OCT) images, and to determine if clinical factors like axial length, central endothelial cell count (CECC) and retinal nerve fibre layer thickness (RNFL) thickness are associated with a positive WDT + DRPT.
Methods: SS-OCT examination was performed in consecutive subjects presenting as new patients in the outpatient clinic aged > 40 years. If at least one eye met the inclusion criteria (anterior chamber angles <20° and anterior chamber depth < 2.
Iris lens distance to predict the risk of intraocular pressure elevation after dark room provocative test.
Graefes Arch Clin Exp Ophthalmol
December 2019
Department of Ophthalmology, Peking Union Medical College Hospital, Peking Union Medical College, Chinese Academy of Medical Sciences, Dongdan Shuaifuyuan 1, Beijing, 100730, China.
Purpose: To investigate if a new ultrasound biomicroscopy (UBM) parameter, iris lens distance (ILD), and its model could predict clinically significant intraocular pressure (IOP) elevation after darkroom provocative test (DRPT).
Methods: Cases with a peripheral anterior chamber depth less than one-fourth corneal thickness were enrolled. All subjects underwent UBM examination and DRPT if possible.
Evaluation of the efficacy of laser peripheral iridoplasty in reversing the darkroom provocative test result in Chinese patients with primary angle closure status post laser iridotomy.
Int J Ophthalmol
June 2015
Department of Ophthalmology, Peking University Third Hospital, Key Laboratory of Vision Loss and Restoration, Ministry of Education, Beijing 100191, China.
Aim: To investigate the efficacy and safety of krypton laser peripheral iridoplasty (LPIP) for Chinese patients with primary angle closure (PAC) or primary angle-closure glaucoma (PACG) status post laser iridotomy in reversing the positive results of the dark room provocative test (DRPT).
Methods: This study was prospective, noncomparative, interventional case series. Thirty-three patients (thirty-eight eyes) with PAC or PACG status post patent laser iridotomy and maintained normal intraocular pressure (IOP) but with positive DRPT results were enrolled.