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The Burden of Cancer and Precancerous Conditions Among Transgender Individuals in a Large Health Care Network: Retrospective Cohort Study.
JMIR Cancer
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Department of Health Outcomes and Biomedical Informatics, University of Florida, 1889 Museum Road, Suite 7000, Gainesville, FL, 32611, United States, 1 352 294-5969.
Background: Disparities in cancer burden between transgender and cisgender individuals remain an underexplored area of research.
Objective: This study aimed to examine the cumulative incidence and associated risk factors for cancer and precancerous conditions among transgender individuals compared with matched cisgender individuals.
Methods: We conducted a retrospective cohort study using patient-level electronic health record (EHR) data from the University of Florida Health Integrated Data Repository between 2012 and 2023.
Randomized Sham Controlled Trial of Targeted Lung Denervation in Patients with COPD (AIRFLOW-3).
Am J Respir Crit Care Med
September 2025
Temple University Hospital, Pulm & Crit Care Medicine, Philadelphia, Pennsylvania, United States.
Rationale: AIRFLOW-3 was a 1:1 randomized, double blind, sham controlled trial of the d'Nerva Targeted Lung Denervation (TLD) System in patients with COPD.
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Methods: AIRFLOW-3 patients were symptomatic (CAT ≥10) with moderate to very severe airflow obstruction (25% ≤ FEV ≤ 80% predicted) and GOLD E status (≥2 moderate or ≥1 severe exacerbation over prior 12 months).
Pulmonary Function in Early-Onset Scoliosis: A Literature Review.
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Seattle Children's Hospital, Seattle, Washington.
» Early-onset scoliosis (EOS) causes restrictive lung disease, secondary to deformation of the thoracic cavity, stiffening of the chest wall, and weakening of the respiratory muscles.» Early spinal fusion has been shown to limit thoracic growth and be associated with poor pulmonary outcomes. This has led to the rise of growth-friendly surgical techniques to maximize thoracic growth.
View Article and Find Full Text PDFNegative Pressure Wound Therapy: An Adjunct in Reconstructing Large Periocular Defects From Necrotizing Fasciitis.
J Craniofac Surg
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Department of Surgery, Cumming School of Medicine, University of Calgary, Calgary, Alberta.
Purpose: To demonstrate the use of negative pressure wound therapy (NPWT) and other reconstructive techniques in the reconstruction of large tissue defects resulting from periocular necrotizing fasciitis (NF).
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Metastatic involvement (MB) of the breast from extramammary malignancies is rare, with an incidence of 0.09-1.3% of all breast malignancies.
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