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http://dx.doi.org/10.1186/s13024-024-00717-9 | DOI Listing |
Water Res
August 2025
School of Environmental and Biological Engineering, Nanjing University of Science and Technology, Nanjing, China. Electronic address:
Global phosphorus (P) resources are facing a depletion crisis, and pyrolysis of P-rich sewage sludge (SS) offers significant resource potential. Optimizing pyrolysis conditions remains key yet challenging for enhancing P retention and bioavailability. This study conducted a correlation-prediction-causation integrated framework (CPCIF) to investigate how heating temperature (HT), heating rate (HR), and retention time (RT) influence total P enrichment rate (BTPE), relative inorganic P transformation rate (BITP), and relative apatite P transformation rate (BAIP) from SS to biochar during pyrolysis.
View Article and Find Full Text PDFNat Commun
September 2025
Shimoda Marine Research Center, University of Tsukuba, Shizuoka, Japan.
Since Hans Driesch's pioneering work in 1891, it has been known that animal embryos can develop into complete individuals even when divided. However, the developmental processes and molecular mechanisms enabling this self-organization remain poorly understood. In this study, we revisit Driesch's experiments by examining the development of isolated 2-cell stage blastomeres in the sea urchin, Hemicentrotus pulcherrimus.
View Article and Find Full Text PDFPLoS Biol
September 2025
Sensory and Motor Systems Neuroscience Group, Korea Brain Research Institute, Daegu, South Korea.
Understanding the neural mechanisms behind short-term memory (STM) errors is crucial for unraveling cognitive processes and addressing deficits associated with neuropsychiatric disorders. This study examines whether STM errors arise from misrepresentation of sensory information or decay in these representations over time. Using 2-photon calcium imaging in the posterior parietal cortex (PPC) of mice performing a delayed match-to-sample task, we identified a subset of PPC neurons exhibiting both directional and temporal selectivity.
View Article and Find Full Text PDFScience
August 2025
Seth Berkley is an adviser to the Pandemic Center and Adjunct Professor at the School of Public Health, Brown University, Providence, RI, USA.
The philosopher Thomas Hobbes famously described life in 1651 as "nasty, brutish, and short." He was undeniably correct, with estimates of average life expectancy in the UK at the time ranging from 37 to 40 years, largely owing to a high infant mortality rate. For example, in London, there were an estimated 251 deaths per 1000 live births.
View Article and Find Full Text PDFFront Immunol
August 2025
Inflammatory Immune-Mediated Chronic Skin Diseases Laboratory, Instituto Maimónides de Investigación Biomédica de Córdoba (IMIBIC), Córdoba, Spain.
Unlabelled: Primary lymphocytic scarring alopecias (PLSAs)-including frontal fibrosing alopecia (FFA), lichen planopilaris (LPP), and central centrifugal cicatricial alopecia (CCCA)-are chronic inflammatory scalp disorders leading to irreversible follicular destruction. Despite overlapping histopathology, their molecular differences remain poorly defined. We performed the first systematic review and transcriptomic meta-analysis of human scalp biopsies in PLSAs (PROSPERO: CRD42024559969), following PRISMA 2020 guidelines.
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