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Background: Poor sleep quality and sleep disorders are more prevalent in individuals with multiple sclerosis (MS) than in the general population. Poor sleep has been correlated with worse MS outcomes. Sleep efficiency (SE) is one of the most sensitive markers of sleep quality. There is very little written about SE and other polysomnography (PSG) parameters and MS measures.
Methods: This is a retrospective review of 280 consecutive individuals with MS evaluated by PSGs and other standardized MS measures over 13 years at a comprehensive MS center. In addition, the cohort was assessed with 2 fatigue scales, the Epworth Sleepiness Scale, and the Expanded Disability Status Scale. A comparison of means test (independent test) and a correlation coefficient () were used.
Results: The PSG measures of SE and Total Sleep Time were significantly different between a group of individuals with MS with a disease duration of more than 5 years vs a group of individuals with MS with a disease duration less than or equal to 5 years. Prevalence of obstructive sleep apnea was 63%, higher than reported in the literature while the prevalence of moderate to severe obstructive sleep apnea was 33.4%, which was lower than reported.
Conclusions: Longer disease duration and worse disability correlate with sleep quality as measured by SE.
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http://dx.doi.org/10.7224/1537-2073.2022-118 | DOI Listing |
Eur Geriatr Med
September 2025
School of Public Health Sciences, University of Waterloo, Waterloo, Canada.
Purpose: Sleep disturbance is prevalent in long-term care facilities (LTCFs), yet there is limited understanding of individual factors predicting changes in sleep within these populations. Our objective was to determine predictors of sleep disturbance in LTCFs and investigate variation in prevalence across facilities in two Canadian provinces-New Brunswick and Saskatchewan.
Method: This retrospective longitudinal cohort study used interRAI comprehensive health assessment data from 2016 to 2021, encompassing 21,394 older adults aged ≥ 65 years across 228 LTCFs.
Chronobiol Int
September 2025
Consultant, Wayzek Science, St Paul, Minnesota, USA.
Understanding how sleep affects the risk of incident chronic conditions in midlife may reinforce the importance of a healthy sleep pattern for healthy aging and cardiometabolic health. The objective of the study was to examine associations of sleep duration and quality with incident obesity, diabetes and metabolic syndrome in mid-aged adults. Participants without obesity ( = 381), diabetes ( = 509), or metabolic syndrome ( = 487) from the Biomarker Projects in Midlife in the United States study were examined separately for baseline sleep duration and quality and their associations with incident obesity, diabetes, or metabolic syndrome after an average follow-up of 12 years.
View Article and Find Full Text PDFNat Sci Sleep
September 2025
Department of Ophthalmology, The Second Affiliated Hospital of Anhui Medical University, Hefei, 230601, People's Republic of China.
Objective: To investigate the prevalence of dry eye disease (DED) among children and adolescents aged 9 to 19 years in Fengyang County, and to explore the associations of sleep duration and social jetlag with DED, with the aim of providing scientific evidence for sleep-based interventions to prevent DED in this population.
Methods: Between November and December 2023, 14 primary and secondary schools were randomly selected in Fengyang County, Chuzhou City, Anhui Province, China. Students from Grade 4 to Grade 12 (aged 9-19 years) were invited to participate.
Front Nutr
August 2025
Department of Gastroenterology, Shanxi Province Cancer Hospital/Shanxi Hospital Affiliated to Cancer Hospital, Chinese Academy of Medical Sciences/Cancer Hospital Affiliated to Shanxi Medical University, Taiyuan, Shanxi, China.
Background: Dietary patterns influence psychological health, systemic inflammation, and gut microbiota composition in colon cancer patients. This study evaluates the associations of the Mediterranean-DASH Intervention for Neurodegenerative Delay (MIND) score and the Dietary Index for Gut Microbiota (DI-GM) with psychological outcomes, inflammatory markers, gut microbiota diversity (Shannon index) and composition (Firmicutes/Bacteroidetes ratio), and tumor biomarkers in colon cancer patients.
Methods: A cross-sectional study was conducted on 630 colon Cancer patients.
Front Allergy
August 2025
Department of Surgery, University of Auckland, Auckland, New Zealand.
Allergic rhinitis (AR) and chronic rhinosinusitis (CRS) are common respiratory conditions that significantly impact patient health and contribute to substantial healthcare burdens. While conventional treatments offer symptom relief, many patients continue to experience persistent symptoms, side effects, or resistance to standard therapies. This highlights the growing need for novel, non-invasive, and sustainable therapeutic strategies to manage chronic airway inflammation.
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