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Unlabelled: We retrospectively study the outcome of left atrial appendage (LAA) preserving maze procedure, focus on thrombus formation in left atrium( LA), postoperative stroke, and LA function.
Patients And Methods: We studied 131 patients (mean age, 68.2y;77 men and 54 women) who underwent maze procedure for atrial fibrillation( Af) between 2008 and 2020. Full maze was performed for 116 patients with long-standing persistent Af or persistent Af. Pulmonary vein isolation alone was performed for 15 patients with paroxysmal Af. The mean follow-up period was 2.9( 10.1-0.4) years.
Results: In perioperative results, there were no death, cerebral infarction, and reoperation in this series. At discharge, 1 year, 3 years, 5 years, and 10 years after the surgery, sinus rhythm was maintained in 92%, 87%, 83%, 77%. Pacemaker was implanted in 8( early 3, late 5) patients. Despite adequate anticoagulant therapy, one patient developed cerebral infarction a month postoperatively. In other patients, there was no cerebral infarction in short-term nor long-term.
Conclusions: The LAA preserving maze procedure was not a risk factor of cerebral infarction under appropriate medication. However, close follow-up is essential.
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Pediatr Res
September 2025
Laboratory of Fetal Neuroprogramming, Institute of Health Sciences, University of O'Higgins, Rancagua, Chile.
Background: Fetal growth restriction (FGR) causes an adaptive redistribution of the cardiac output towards sustained cerebral vasodilation. However, the consequences of FGR and cerebral vasodilatation due to fetal hypoxia on the blood-brain barrier (BBB) are still poorly studied. This study assesses BBB permeability in the neonatal cortex of pups gestated under intrauterine hypobaric hypoxia.
View Article and Find Full Text PDFInt J Surg Case Rep
September 2025
Arai Hospital, 2-2-28, Kukichuo, Kuki-shi, Saitama, 346-0003, Japan.
Introduction And Importance: Transverse mesocolic hernia is an extremely rare type of internal hernia, with only a limited number of cases reported to date. In this case report, we present a geriatric patient with a transverse mesocolic hernia who was successfully treated with emergent laparoscopic surgery.
Case Presentation: An 89-year-old male patient presented with abdominal pain and distension that had begun the previous day.
Clin Neuroradiol
September 2025
Department of Diagnostic and Interventional Neuroradiology, Inselspital, Bern University Hospital, University of Bern, Bern, Switzerland.
Background: Pediatric acute ischemic stroke is a rare yet severe condition with multifactorial etiology, often associated with vasculopathies. Endovascular intervention in children with focal cerebral arteriopathy is seldom reported.
Purpose: Our aim was to report feasibility of intracranial rescue stenting for the management of pediatric focal cerebral arteriopathy with flow-limiting stenosis.
Brain Behav
September 2025
Department of Neurology, The First Affiliated Hospital of Harbin Medical University, Harbin, Heilongjiang, P. R. China.
Background: Ischemic stroke (IS) is a common neurological disease with a significant financial burden but lacks effective drugs. This study sought to explore the mechanisms underlying MAP kinase-interacting serine/threonine-protein kinase 2 (MKNK2), a gene enriched in the hypoxia-inducible factor-1 (HIF-1) signaling, in IS-related neurological injury.
Methods: Middle cerebral artery occlusion/reperfusion (MCAO/R) and oxygen-glucose deprivation/reoxygenation (OGD/R) models were used in vivo and in vitro.
Cureus
August 2025
Division of Thoracic and Cardiovascular Surgery, Niigata University Graduate School of Medical and Dental Sciences, Niigata, JPN.
Cerebral infarction is a rare but serious complication after pulmonary resection for lung cancer. A 78-year-old man with hypertension and diabetes underwent video-assisted thoracoscopic right middle lobectomy for stage IA2 adenocarcinoma. On postoperative day 1, he developed acute right hemiparesis and motor aphasia.
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