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Purpose: Joint space width (JSW) is a common metric used to evaluate joint structure on plain radiographs. For the hand, quantitative techniques are available for evaluation of the JSW of finger joints; however, such techniques have been difficult to establish for the trapeziometacarpal (TMC) joint. This study aimed to develop a validated method for measuring the radiographic joint space of the healthy TMC joint.
Approach: Computed tomographic scans were taken of 15 cadaveric hands. The location of a JSW analysis region on the articular surface of the first metacarpal was established in 3D space and standardized in a 2D projection. The standardized region was applied to simulated radiographic images. A correction factor was defined as the ratio of the CT-based and radiograph-based joint space measurements. Leave-one-out validation was used to correct the radiograph-based measurements. A t-test was used to evaluate the difference between CT-based and corrected radiograph-based measurements ().
Results: The CT-based and radiograph-based measurements of JSW were and , respectively. The correction factor for radiograph-based joint space was . Before correction, the difference between the CT-based and radiograph-based joint space was 1.43 mm [95% CI: ; ]. After correction, the difference was [95% CI: ; ].
Conclusions: Corrected measurements of radiographic TMC JSW agreed well with CT-measured JSW. With validation, the developed methodology has potential for automated and accurate radiographic measurement of TMC JSW.
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http://www.ncbi.nlm.nih.gov/pmc/articles/PMC10911767 | PMC |
http://dx.doi.org/10.1117/1.JMI.11.2.024001 | DOI Listing |
Neural Netw
September 2025
Shanghai Maritime University, Shanghai, 201306, China. Electronic address:
Cross-modal hashing aims to leverage hashing functions to map multimodal data into a unified low-dimensional space, realizing efficient cross-modal retrieval. In particular, unsupervised cross-modal hashing methods attract significant attention for not needing external label information. However, in the field of unsupervised cross-modal hashing, there are several pressing issues to address: (1) how to facilitate semantic alignment between modalities, and (2) how to effectively capture the intrinsic relationships between data, thereby constructing a more reliable affinity matrix to assist in the learning of hash codes.
View Article and Find Full Text PDFPLoS One
September 2025
Department of design fundamentals, Faculty of Mechanical Engineering, Industrial University of Ho Chi Minh City, Ho Chi Minh City, Vietnam.
The slider-crank mechanism (SCM) is fundamental to various mechanical systems. However, optimizing its dynamic performance remains a pressing challenge due to excessive torque, joint reactions, and energy consumption. This study introduces two key innovations to address these challenges: (1) the integration of springs into SCM to optimize dynamic performance and (2) a novel hybrid optimization approach combining the Conjugate Direction with Orthogonal Shift (CDOS) method and Parameter Space Investigation (PSI).
View Article and Find Full Text PDFJ Am Chem Soc
September 2025
Institute of Functional Nano & Soft Materials (FUNSOM), Jiangsu Key Laboratory for Carbon-Based Functional Materials & Devices, Soochow University, Suzhou 215123, Jiangsu P. R. China.
Advances in molecular analysis and characterization techniques should revolutionize the methods for scientific exploration across physics, chemistry, and biology, fundamentally overturning our understanding of interactions and processes that govern molecular behavior at the microscopic level. Currently, the absence of a molecular analysis method that can both quantify molecules and achieve single-molecule spatial resolution hinders our study of complex molecular systems in sorption and catalysis. Here, we propose a quantitative analysis strategy for small molecules confined in ZSM-5, a zeolite material extensively used in catalysis and gas separation, based on low-dose transmission electron microscopy.
View Article and Find Full Text PDFCase Rep Rheumatol
August 2025
Department of Rheumatology and Internal Medicine, Kamitsuga General Hospital, Kanuma, Tochigi, Japan.
Nontuberculous (NTM) infections affecting musculoskeletal structures are rare, particularly in patients with well-controlled rheumatoid arthritis (RA). This case is reported to highlight the potential risk of focal tenosynovitis due to following intra-articular glucocorticoid injection. A 79-year-old man with well-controlled RA developed tenosynovitis with bone destruction in the right index finger metacarpophalangeal joint following a single intra-articular injection of triamcinolone acetonide.
View Article and Find Full Text PDFPrev Vet Med
September 2025
World Organisation for Animal Health (WOAH) Sub-Regional Representation for South East Asia, Bangkok 10400, Thailand.
Foot and mouth disease (FMD) remains endemic in several countries across Southeast Asia, China, and Mongolia (SEACFMD region), posing an ongoing threat to livestock and trade. This study aimed to investigate the epidemiological characteristics and analyze the spatial and temporal distribution of FMD outbreaks reported across the SEACFMD region. FMD outbreak and virus lineage data from 2015 to 2023 were utilized.
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