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http://dx.doi.org/10.1161/CIRCULATIONAHA.123.065414 | DOI Listing |
JMIR Res Protoc
September 2025
University of Nevada, Las Vegas, Las Vegas, NV, United States.
Background: In-hospital cardiac arrest (IHCA) remains a public health conundrum with high morbidity and mortality rates. While early identification of high-risk patients could enable preventive interventions and improve survival, evidence on the effectiveness of current prediction methods remains inconclusive. Limited research exists on patients' prearrest pathophysiological status and predictive and prognostic factors of IHCA, highlighting the need for a comprehensive synthesis of predictive methodologies.
View Article and Find Full Text PDFMenopause
September 2025
Department of Obstetrics and Gynecology, Gaziantep University School of Medicine, Gaziantep, Turkey.
Objective: Our study aimed to compare premenopausal and postmenopausal women in terms of choroidal thickness and choroidal vascularity index.
Methods: This cross-sectional study included 96 eyes of 96 participants, comprising 48 premenopausal and 48 postmenopausal women. Enhanced depth image optical coherence tomography (EDI-OCT) was used to visualize the choroid.
PLoS One
September 2025
Department of Biomedical Data Intelligence, Graduate School of Medicine, Kyoto University, Kyoto, Japan.
Capturing the dynamic changes in patients' internal states as they approach death due to fatal diseases remains a major challenge in understanding individual pathologies and improving end-of-life care. However, existing methods primarily focus on specific test values or organ dysfunction markers, failing to provide a comprehensive view of the evolving internal state preceding death. To address this, we analyzed electronic health record (EHR) data from a single institution, including 8,976 cancer patients and 77 laboratory parameters, by constructing continuous mortality prediction models based on gradient-boosting decision trees and leveraging them for temporal analyses.
View Article and Find Full Text PDFPLoS One
September 2025
Biaoxin Science & Technology (Beijing) Co., Ltd, Beijing, China.
This study examines China's national standard development from 2001 to 2023. Using machine splitting and location assignment technology, the Dagum Gini coefficient and its decomposition methods, and traditional and spatial Markov chain estimation methods, we identify the spatiotemporal disparities and dynamic transition characteristics of the contribution levels to national standard development across China's eight comprehensive economic zones. The findings provide a reference for promoting regional coordinated sustainable development and high-quality economic transformation.
View Article and Find Full Text PDFJ Alzheimers Dis
September 2025
Frontotemporal Disorders Unit, Department of Neurology, Massachusetts General Hospital and Harvard Medical School, Charlestown, MA, USA.
Compared with more typical late-onset Alzheimer's disease (AD), the mechanisms of young-onset AD (YOAD; age of symptom onset <65 years) remain less understood. Using resting-state functional MRI data and dynamic causal modeling techniques, Sacu et al. demonstrate that individuals with YOAD (amnestic AD or posterior cortical atrophy) exhibit alterations in effective (i.
View Article and Find Full Text PDF