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The excellent image-generation ability of generative adversarial networks (GANs) has been widely used. However, training a GAN requires large-scale data support, which hinders in-depth development. Therefore, the research on stable training of GANs under limited data conditions is helpful to further expand the application scenarios. To solve this problem, a new network based on a dual-ways discriminator structure is designed, used to eliminate the problem that a single discriminator model is prone to overfitting under the condition of limited data. Then, the problem that the traditional data augmentation strategy is limited to pixel space and lacks attention to the overall structure and contour of the image is analyzed. An adaptive dynamic data augmentation strategy based on the Laplace convolution kernel is proposed from the frequency domain space, which realizes the purpose of implicitly increasing the training data in the training process. This new designed module improves the performance of the generative adversarial network. Through extensive experiments, it was confirmed that the new network, named FD-GAN, achieved prefer image generation ability, and its Fid score reached 4.58, 12.007, and 10.382 in the AFHQ-Cat, AFHQ-Dog, and TankDataSet datasets, respectively.
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http://dx.doi.org/10.1016/j.heliyon.2024.e25250 | DOI Listing |
Comput Methods Biomech Biomed Engin
September 2025
Institute of Radio Physics and Electronics, University of Calcutta, Kolkata, India.
Parkinson's disease (PD) is a neurodegenerative condition that impairs motor functions. Accurate and early diagnosis is essential for enhancing well-being and ensuring effective treatment. This study proposes a deep learning-based approach for PD detection using EEG signals.
View Article and Find Full Text PDFMed Phys
September 2025
Department of Medical Physics and Biomedical Engineering, University College London, London, UK.
Background: Integrated mode proton imaging is a clinically accessible method for proton radiographs (pRads), but its spatial resolution is limited by multiple Coulomb scattering (MCS). As the amplitude of MCS decreases with increasing particle charge, heavier ions such as carbon ions produce radiographs with better resolution (cRads). Improving image resolution of pRads may thus be achieved by transferring individual proton pencil beam images to the equivalent carbon ion data using a trained image translation network.
View Article and Find Full Text PDFJ Vis Exp
August 2025
Department of Computer Science and Engineering, Gokaraju Rangaraju Institute of Engineering and Technology, Hyderabad, India.
Deepfakes pose critical threats to digital media integrity and societal trust. This paper presents a hybrid deepfake detection framework combining Convolutional Neural Networks (CNNs) and Generative Adversarial Networks (GANs) to address challenges in scalability, generalizability, and adversarial robustness. The framework integrates adversarial training, a temporal decay analysis model, and multimodal detection across audio, video, and text domains.
View Article and Find Full Text PDFJ Chem Phys
September 2025
Department of Chemistry, Chicago Center for Theoretical Chemistry, Institute for Biophysical Dynamics, and James Franck Institute, The University of Chicago, 5735 S. Ellis Ave., SCL 123, Chicago, Illinois 60637, USA.
Molecular dynamics simulations are essential for studying complex molecular systems, but their high computational cost limits scalability. Coarse-grained (CG) models reduce this cost by simplifying the system, yet traditional approaches often fail to maintain dynamic consistency, compromising their reliability in kinetics-driven processes. Here, we introduce an adversarial training framework that aligns CG trajectory ensembles with all-atom (AA) reference dynamics, ensuring both thermodynamic and kinetic fidelity.
View Article and Find Full Text PDFACS Omega
September 2025
Division of Pharmaceutical Chemistry, Faculty of Pharmaceutical Sciences, Khon Kaen University, Khon Kaen 40002, Thailand.
Dengue virus remains a significant global health threat, imposing a substantial disease burden on nearly half of the world's population. The urgent need for effective antiviral therapeutics, including therapeutic peptides targeting the Dengue virus, is critical in the current healthcare landscape. However, the availability of anti-Dengue peptides (ADPs) data remains limited in existing data sets, posing a challenge for computational modeling and discovery.
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