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See also the commentary by Sitek in this issue.
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http://www.ncbi.nlm.nih.gov/pmc/articles/PMC10982815 | PMC |
http://dx.doi.org/10.1148/ryai.230147 | DOI Listing |
Med Biol Eng Comput
September 2025
Department of Computer Science, Università degli Studi di Bari Aldo Moro, Bari, Italy.
Fetal standard plane detection is essential in prenatal care, enabling accurate assessment of fetal development and early identification of potential anomalies. Despite significant advancements in machine learning (ML) in this domain, its integration into clinical workflows remains limited-primarily due to the lack of standardized, end-to-end operational frameworks. To address this gap, we introduce FetalMLOps, the first comprehensive MLOps framework specifically designed for fetal ultrasound imaging.
View Article and Find Full Text PDFProc IEEE Comput Soc Conf Comput Vis Pattern Recognit
June 2025
The advancement of Multimodal Large Language Models (MLLMs) has enabled significant progress in multi-modal understanding, expanding their capacity to analyze video content. However, existing evaluation benchmarks for MLLMs primarily focus on abstract video comprehension, lacking a detailed assessment of their ability to understand video compositions, the nuanced interpretation of how visual elements combine and interact within highly compiled video contexts. We introduce VidComposition, a new benchmark specifically designed to evaluate the video composition understanding capabilities of MLLMs using carefully curated compiled videos and cinematic-level annotations.
View Article and Find Full Text PDFJMIR AI
September 2025
Department of Anesteshiology, Perioperative and Pain Medicine, Mount Sinai, New York, NY, United States.
Background: Clinical notes house rich, yet unstructured, patient data, making analysis challenging due to medical jargon, abbreviations, and synonyms causing ambiguity. This complicates real-time extraction for decision support tools.
Objective: This study aimed to examine the data curation, technology, and workflow of the named entity recognition (NER) pipeline, a component of a broader clinical decision support tool that identifies key entities using NER models and classifies these entities as present or absent in the patient through an NER assertion model.
PLoS Genet
September 2025
Department of Veterinary Population Medicine, College of Veterinary Medicine, University of Minnesota, St. Paul, Minnesota, United States of America.
MicroRNAs (miRNAs) are essential regulators of gene expression, yet few comprehensive databases exist for miRNA expression in non-model species, limiting our ability to characterize their roles in gene regulation, development, and disease. Similarly, isomiRs - length and sequence isoforms of canonical miRNAs with potentially altered regulatory targets and functions - have received even less attention in non-model species, including the horse, leaving a critical gap in our understanding of their biological significance. To address these challenges, we developed an open-source, containerized pipeline for identifying and quantifying miRNAs and isomiRs (FARmiR: Framework for Analysis and Refinement of miRNAs), and an associated interactive browser (AIMEE: Animal IsomiR and MiRNA Expression Explorer).
View Article and Find Full Text PDFIntroduction: The Clinical Genome Resource (ClinGen) Von Hippel-Lindau (VHL) Variant Curation Expert Panel (VCEP) has created variant classification specifications tailored to the gene, including phenotype-driven and evidence-based criteria, somatic and germline mutational hotspots, functional and in-silico data.
Materials And Methods: Using the American College of Medical Genetics and Genomics (ACMG) guidance and the ClinGen Sequence Variant Interpretation (SVI) recommendations, the VCEP made substantial modifications to eight evidence codes (PVS1, PS3, PS4, PM1, BS2, BS3, BS4, BP5), while 14 had minor or no changes and 6 were not used (PM3, PP2, BP1, PP4, PP5/BP6). The VHL VCEP applied two literature sets of over >428 papers in Clinical Interpretations of Variants in Cancer (CIViC) and >8700 structured annotations using Hypothesis.