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Article Abstract
A series of β-ketoenamines was synthesized from various phenacyl sulfoxides bearing 1-methyl-1-tetrazole and oximes in moderate to excellent yields. The proposed mechanism involved the generation of α-sulfines from sulfoxides through thermolytic elimination, regiospecific formal [3 + 2] annulations, and elimination of SO. This protocol provides convenient access to a variety of synthetically valuable -unprotected β-enaminones with absolute selectivity.
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