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Endodontic pain, a common complication after root canal treatment, affects 2.5% to 60% of patients. Therefore, it is of interest to compare apical negative pressure irrigation (EndoVac) with conventional needle irrigation to assess their impact on postoperative pain in permanent anterior teeth with symptomatic irreversible pulpitis. Fifty patients were randomly assigned to either the EndoVac or needle irrigation group. Pre and post-operative pain levels were assessed using a Visual Analog Scale and the amount of Ibuprofen taken was recorded. At 12-, 24-, and 48-hour intervals, the EndoVac group reported significantly less pain than the needle irrigation group. The needle irrigation group also required more Ibuprofen. The apical negative pressure irrigation system (EndoVac) resulted in significantly less postoperative pain and reduced the need for analgesic medication than the conventional needle irrigation protocol.
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http://dx.doi.org/10.6026/973206300191129 | DOI Listing |
World J Methodol
December 2025
Department of Periodontics, Sudha Rustagi College of Dental Sciences and Research, Faridabad 121002, Haryāna, India.
Background: Advanced materials and techniques are used to successfully manage the apexification of immature teeth with open apices. The use of mineral trioxide aggregate (MTA), bioceramic sealers, and sodium hypochlorite (NaOCl), combined with internal heating and ultrasonic activation, ensures that canals are cleaned, disinfected, and sealed properly. Magnification devices, such as dental operating microscopes (DOM), provide precise visualization for accurate material placement, while the micro apical placement system ensures void-free MTA delivery.
View Article and Find Full Text PDFBMC Ophthalmol
September 2025
Department of Ophthalmology, Tongji Hospital, School of Medicine, Tongji University, No.389 Xincun Road, Putuo District, Shanghai, 200065, China.
Purpose: To evaluate the clinical efficacy and safety of a novel shape-memory Bi-hook device in facilitating antegrade stent implantation for canalicular laceration repair.
Methods: In this retrospective comparative study, 76 patients (76 eyes) with canalicular laceration were enrolled: 39 patients (39 eyes) underwent Bi-hook-assisted stent implantation (Bi-hook group) and 37 patients received conventional Ritleng stent intubation (control group). The Bi-hook device was fabricated using a thermally shaped 0.
Life (Basel)
August 2025
Institute of Radiology, Department of Medicine-DIMED, University of Padova, Via Giustiniani 2, 35128 Padova, Italy.
Ultrasound-guided percutaneous interventions are well-established as effective treatments for shoulder calcific tendinopathy. In this work, we modified the conventional double-needle approach by incorporating a closed-circuit irrigation system and assessed the procedure's clinical and radiological outcomes. We enrolled prospectively 24 patients (10 males; median age 54 years, IQR: 50-62) with painful calcific tendonitis of the shoulder between October 2023 and March 2024.
View Article and Find Full Text PDFJ Cardiol
August 2025
Cardiovascular Division, Department of Medicine, Vanderbilt University Medical Center, Nashville, TN, USA.
Radiofrequency catheter ablation (RFCA) is a common treatment option for ventricular arrhythmias (VA). Risks of RFA for VA include emboli and bleeding complications. In contrast to atrial fibrillation ablation procedures, for which anticoagulation therapy is relatively well standardized, peri-procedural antithrombotic therapy practices for RFCA of VA vary among laboratories and remains an area of investigation.
View Article and Find Full Text PDFSci Rep
August 2025
Department of Molecular Pathology, The Affiliated Cancer Hospital of Zhengzhou University, Henan Cancer Hospital, Zhengzhou, 450008, China.
To address inherent limitations of standard diagnostic procedures for lung cancer, like long turn-around-time and the need for sufficient samples for analysis, we innovatively integrated traditional smear cytology (TSC) with quantitative polymerase chain reaction (qPCR) assays on micro cell samples (MCSs) for the diagnosis of lung cancer. All patients underwent TSC and qPCR assays targeting 11 genes based on different MCSs, including samples obtained by flushing needles used for endobronchial ultrasound biopsies and percutaneous aspiration biopsies of lung in 38 cases (G1) and 108 cases (G2), and lavage fluid samples obtained by bronchoalveolar lavage in 38 cases (G3). With clinical diagnosis and pathological biopsy as diagnostic gold standard, the diagnostic value of these MCSs were explored.
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