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Article Abstract
Biological activity and bioactive compound content in sea cucumbers was assessed, considering , , , and as species and intestine, muscle band, respiratory tree, body wall, and gonads as tissues. had the lowest content in phenolic compounds and antioxidant activity in contrast to species. In the respiratory tree, the highest phenolic concentration was recorded in , 76.4 ± 1.2 mg GAE/100 g dw vs. 21.0-49.0 mg GAE/100 g dw in the other species. had the highest DPPH and FRAP results in the gonads, 13.6 ± 0.7 mg AAE/100 g dw vs. 2.6-3.5 mg AAE/100 g dw and 27.1 ± 0.3 μmol Fe/g dw vs. 8.0-15.9 μmol Fe/g dw, respectively. Overall, biomass presented the highest anti-inflammatory activity levels and the lowest anti-inflammatory levels. The respiratory tree was the most anti-inflammatory (measured by the inhibition of cyclooxygenase-2, COX-2) tissue in and (also the muscle band in this case), 76.3 ± 6.3% and 59.5 ± 3.6% COX-2 inhibition in 1 mg/mL aqueous extracts, respectively. The results demonstrated a variable bioactive potential and advantage in targeting antioxidant properties in the muscle band and anti-inflammatory activity in the respiratory tree, which may constitute a starting point for a biorefinery approach envisaging multiple applications.
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| http://dx.doi.org/10.3390/foods13010035 | DOI Listing |
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