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To evaluate the effectiveness of augmented reality (AR) game based on -back training paradigm as a training tool for working memory (WM) of Chinese healthy older adults. One hundred eighteen older adults self-assessed as healthy were included in this study. Individuals were randomly divided into an intervention group ( = 57) and a control group ( = 61). Interventions, consisting of a 30-minute AR game-based training and a 30-minute health science program, were administered three times per week for 4 weeks, whereas the control group was required to view a 60-minute health science program three times per week for 4 weeks. Tests, Digit Span, Corsi Block-Tapping Task (CBT), and Stroop Color and Word Test (SCWT), were conducted for all participants before and after the experiment, and the game accuracy rate of the intervention group before and after intervention was recorded. There was a statistically significant difference in terms of both CBT indicators, CBT forward span ( = -2.835, = 0.005) and CBT backward span ( = 3.285, = 0.001), and the SCWT indicator of Stroop Words Test (SW) ( = -1.894, = 0.048) in the two groups. The intervention group showed significant improvements in the game accuracy of both medium level ( = -3.535, < 0.05) and of high level ( = -3.953, < 0.05). In addition, differences were observed in subgroup analysis in the accuracy of medium level ( = 6.218, < 0.05) and high level ( = 8.002, < 0.05) among older people with different levels of education. AR game based on -back training paradigm could improve WM of Chinese older adults, showing potential for wider promotion and adoption.
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http://dx.doi.org/10.1089/g4h.2022.0183 | DOI Listing |
JCI Insight
September 2025
Diabetes & Metabolism Research Center, University of Utah, Salt Lake City, United States of America.
Impaired muscle regrowth in aging is underpinned by reduced pro-inflammatory macrophage function and subsequently impaired muscle cellular remodeling. Macrophage phenotype is metabolically controlled through TCA intermediate accumulation and activation of HIF1A. We hypothesized that transient hypoxia following disuse in old mice would enhance macrophage metabolic inflammatory function thereby improving muscle cellular remodeling and recovery.
View Article and Find Full Text PDFJ Med Internet Res
September 2025
Institute of Social Medicine, Occupational Health and Public Health (ISAP), Medical Faculty, University of Leipzig, Leipzig, Germany.
Background: The loss of a loved one is a common yet stressful event in later life. Internet- and mobile-based interventions have been proposed as an effective treatment approach for individuals with prolonged grief.
Objective: The AgE-health study aimed to investigate the efficacy of an eHealth intervention, trauer@ktiv, in reducing prolonged grief symptoms in a sample of older adults.
Soc Work Public Health
September 2025
Department of Healthcare Management, Çankırı Karatekin University, Çankırı, Türkiye.
This study investigates socioeconomic disparities in chronic respiratory diseases and the factors contributing to these inequalities, using data from the 2019 Turkish Health Survey. Multivariate logistic regression and Oaxaca-Blinder decomposition analyses reveal that 13.10% of adults aged 25 and older in Turkey suffer from chronic respiratory diseases, with a significantly higher prevalence among lower socioeconomic status (SES) individuals.
View Article and Find Full Text PDFJASA Express Lett
September 2025
Department of Audiology and Speech-Language Pathology, University of North Texas, Denton, Texas 76201,
Misophonia is a condition characterized by intense negative emotional reactions to trigger sounds and related stimuli. In this study, adult listeners (N = 15) with a self-reported history of misophonia symptoms and a control group without misophonia (N = 15) completed listening judgements of recorded misophonia trigger stimuli using a standard scale. Participants also completed an established questionnaire of misophonia symptoms, the Misophonia Questionnaire (MQ).
View Article and Find Full Text PDFJAMA Netw Open
September 2025
Department of Psychiatry, Psychosomatics, and Psychotherapy, University of Lübeck, Lübeck, Germany.
Importance: Patients with inflammatory rheumatic diseases (IRDs) frequently experience psychological distress; however, access to psychological support remains limited.
Objective: To investigate the effectiveness of a digital psychological intervention for individuals with IRDs.
Design, Setting, And Participants: Participants aged 18 years or older were recruited across Germany between February 22 and June 4, 2024, if they had been diagnosed with rheumatoid arthritis, psoriatic arthritis, or systemic lupus erythematosus and reported psychological distress and reduced quality of life.