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Unlabelled: Sinus of Valsalva aneurysm (SVA) is a rare cardiac anomaly that commonly originates from the right or noncoronary sinuses and rarely from the left sinus. SVA is usually diagnosed in the setting of clinical sequelae of a rupture. We herein report a case of an unruptured left SVA presenting as acute myocardial infarction. A 54-year-old woman with a history of radical operation for patent ductus arteriosus in childhood was transferred to our hospital. An electrocardiogram indicated extensive myocardial ischemia with ST elevation. Urgent coronary angiography was performed but was unable to identify the left coronary artery. Subsequent aortography and computed tomography revealed a large SVA originating from the left sinus and compressing the left coronary artery. The patient died after approximately one month of intensive care, including mechanical circulatory support and coronary artery bypass grafting. Autopsy confirmed that the left main coronary trunk was stretched and compressed by the SVA and revealed unexpected atherosclerosis in the left anterior descending artery. Although a left SVA is an extremely rare anomaly, it occasionally provokes fatal myocardial infarction. Since an SVA might hinder performing percutaneous coronary intervention, cardiac surgery should be considered when myocardial ischemia is recognized.
Learning Objective: We herein report a case of an unruptured left sinus of Valsalva aneurysm (SVA) with acute myocardial infarction. Urgent percutaneous coronary intervention (PCI) was unsuccessful, as the left coronary artery was compressed by the SVA. The patient died after intensive care, including coronary artery bypass grafting (CABG). SVA, especially from the left sinus, is extremely rare but occasionally provokes myocardial infarction by compressing the coronary arteries. Because SVA might hinder PCI, CABG should be considered when myocardial ischemia is recognized.
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http://dx.doi.org/10.1016/j.jccase.2023.10.003 | DOI Listing |
JACC Case Rep
September 2025
Meyer University Hospital, Florence, Italy.
Background: Single coronary artery is a rare congenital anomaly. Its coexistence with coronary artery fistula is exceedingly uncommon.
Case Summary: A 61-year-old woman with no cardiovascular risk factors underwent her first cardiological evaluation after incidental detection of atrial fibrillation.
J Craniofac Surg
September 2025
Department of Otorhinolaryngology, University of Health Science, Ankara Bilkent City Hospital, Ankara.
This retrospective study aims to evaluate paranasal computed tomography (CT) scans that were previously obtained as part of routine preoperative assessment in patients who underwent rhinoplasty for aesthetic purposes, focusing on the prevalence of sinonasal anatomic variations and high septal deviations in cases without nasal axis deformity. The study included 274 patients who underwent rhinoplasty for aesthetic reasons. Preoperative CT images of the patients were evaluated in axial slices with a thickness of 0.
View Article and Find Full Text PDFCureus
September 2025
Interventional Cardiology, University of Rochester Medical Center, Rochester, USA.
Sinus venosus atrial septal defects (ASDs) are rare congenital anomalies that result from an abnormality of the junction between the right atrium, superior vena cava (SVC), and pulmonary veins. This defect causes right-to-left shunting, which can lead to progressive right heart enlargement. We present a case of a 59-year-old man with a history of hypertension and hyperlipidemia who presented with dyspnea and newly diagnosed atrial flutter.
View Article and Find Full Text PDFThromb J
September 2025
C-Care International Hospital Kampala, Plot 4686 Barnabas Road, Kampala, Uganda.
Background: Majority of people with "kissing carotids", an anatomical variation of the cervical carotid arteries showing tortuosity, kinking or coiling and coming in proximity at the midline are asymptomatic. Less than 1% of the general population have Protein S Deficiency. This report discusses a rare case of a young female with co-existent Protein S deficiency and kissing carotids, who presented with sequential thrombosis in both arterial and venous cerebral circulation systems and further discusses potential mechanisms of arterial thrombosis in Protein S deficiency and medical options for secondary stroke prophylaxis in this context.
View Article and Find Full Text PDFAnn Med Surg (Lond)
September 2025
Department of Thoracic and Cardiac Surgery, Puren Hospital affiliated to Wuhan University of Science and Technology School of Medicine, Wuhan, China.
Introduction And Importance: Cardiac atherosclerotic disease (CAD), the leading cause to cardiovascular disease-related death, coexisting with cardiac myxoma, the commonest benign primary cardiac neoplasm, is rare. The treatment of the comorbidity is complicated due to the rarity and inexperience.
Case Presentation: A 65-year old male patient with intermittent chest tightness and shortness of breath for 10 years was admitted for further work-up.