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Purpose: This is the first study to assess the impact of an online microsurgical testicular sperm extraction (mTESE) masterclass. We: 1) describe the masterclass's scientific content; 2) appraise the participants' acquisition of knowledge; 3) gauge whether the extent of improvement of the participants' knowledge/skills was influenced by demographic/professional attributes; and 4) evaluate the participants' satisfaction.
Materials And Methods: This masterclass comprised five didactic lectures followed by 4 case discussions. Online surveys assessed the above objectives using a baseline questionnaire including demographics and past mTESE experience/training, a 24-question pre- and post-quiz, and a satisfaction questionnaire.
Results: Participants were between 20-70 years old, with 80.37% males, mainly from Asia, Africa, and Europe, from clinical backgrounds (69.3%), and in public practice (64.4%). Half the sample reported no past mTESE training and very low skills, ≈60% wanted considerably more training, and 50% felt that good training was not readily available. Satisfaction was 98% to >99%. Pre- and post-quiz comparisons confirmed remarkable improvements in knowledge/skills, exhibiting five striking characteristics. Improvements were a) Broad , across 19 of the 24 mTESE questions; b) Deep, of magnitude, as pre-/post-quiz scores improved from mean 13.71±4.13 to 17.06±4.73; c) Highly significant, consistently with p-values <0.001; d) Inclusive , all participants enhanced their mTESE knowledge/skills regardless of demographic/professional attributes; and, e) Differential, , non-clinical/clinical participants improved, but the former improved relatively significantly more, those with ≤5-year experience improved significantly more than those with >5-year, those in public practice significantly more than private practice participants, and those with lower self-rating in performing mTESE significantly more than those with higher self-rating.
Conclusions: The masterclass was successful with very high satisfaction levels, and markedly improved mTESE knowledge/skills among the participants. Global Andrology Forum's model can be adopted by organizations with similar goals. Future research needs to evaluate such training to develop a practically non-existent evidence base.
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http://dx.doi.org/10.5534/wjmh.230195 | DOI Listing |
Ann Med Surg (Lond)
September 2025
Urology, King Faisal Specialist Hospital and Research Centre, Riyadh, Saudi Arabia.
Introduction: Testicular sperm extraction (TESE) is a common procedure for retrieving sperm in men with azoospermia. However, the success rates of a second TESE following an initial unsuccessful attempt remain low. This study aims to develop and evaluate a machine learning algorithm to predict the success of a second microsurgical TESE (microTESE).
View Article and Find Full Text PDFJ Pers Med
August 2025
Third Department of Urology, Attikon University Hospital, School of Medicine, National and Kapodistrian University of Athens, 12462 Athens, Greece.
Prostate cancer (PCa) is the second most frequently diagnosed malignancy in men worldwide. Although traditionally considered a disease of older men, the incidence of early-onset PCa (diagnosis < 55 years) is steadily rising. Advances in screening and therapy have significantly improved survival, creating a growing cohort of younger survivors for whom post-treatment quality of life-notably reproductive function-is paramount.
View Article and Find Full Text PDFArch Ital Urol Androl
August 2025
Department of Urology, Faculty of Medicine, Universitas Brawijaya, Saiful Anwar General Hospital, Malang.
Introduction: Varicocele affects 10-15% of adult males, and is linked to infertility (35%) and testicular pain (10%). Microsurgical varicocelectomy (MV) is considered the gold standard treatment due to its low complication rates and superior anatomical outcomes. However, conventional MV using a 2D exoscope presents limitations in image depth and surgeon ergonomics.
View Article and Find Full Text PDFFertil Steril
July 2025
Vita-Salute San Raffaele University, Milan, Italy; Division of Experimental Oncology/Unit of Urology, Urological Research Insitute, IRCCS Ospedale San Raffaele, Milan, Italy. Electronic address:
Objective: To study real-life rates and predictors of sperm retrieval (SR) in men with nonmosaic Klinefelter syndrome (KS) seeking medical help for primary male factor couples' infertility.
Design: Multicenter, retrospective, cohort study.
Subjects: Data analysis from 383 non-Finnish, White-European, nonmosaic KS men with nonobstructive azoospermia (NOA) undergoing testicular sperm extraction (TESE) between 2008 and 2024 at 12 tertiary referral centers in Italy.
Investig Clin Urol
July 2025
Department of Infertility and Sexual Medicine, The Third Affiliated Hospital, Sun Yat-Sen University, Guangzhou, China.
Purpose: To propose a novel surgical approach for managing inflammatory adhesions of the tunica vaginalis (TV) during vasoepididymostomy (VE), and to report surgical outcomes.
Materials And Methods: A T-shaped incision of the TV was used to expose the epididymis and vas deferens in cases with adhesions between the TV and the testis. We retrospectively analyzed data from five patients who underwent microsurgical VE for obstructive azoospermia (OA) secondary to epididymal obstruction.