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Present study analyzed the seasonal and spatial distribution patterns, sources, and ecological risks of seven heavy metals (Cr, Fe, Ni, Cu, Zn, Cd and Pb) in the sediments of River Ganges, finding that the majority of concentrations were lithologic, except for Cd, which was significantly higher than background standards. Elevated values of geochemical indices viz. I, CF, RI, C, mC, HQ, mHQ, and P suggest moderate to high ecological risk in the benthic environment and its organisms due to the synergistic effect of heavy metals. The PEC-Q revealed 8-10 % toxicity in the upstream and downstream sites, due to the influence of agricultural activities. Multivariate statistical techniques (PCM and PCA) indicated that Cd and Pb predominantly originated from anthropogenic sources, while other metals primarily derived from geological background. These geochemical findings may help to understand the potential risks and recommend strategies to mitigate the effects of metallic contamination in river sediments.
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http://dx.doi.org/10.1016/j.marpolbul.2023.115910 | DOI Listing |
Environ Monit Assess
September 2025
Department of Zoology, Faculty of Biology, University of Sevilla, Av. Reina Mercedes 6, 41012, Seville, Spain.
Marine ecosystems, particularly estuaries, are increasingly threatened by anthropogenic pressures. The Odiel Estuary has suffered severe contamination from acid mine drainage and industrial activities. Since 1986, mitigation efforts have been implemented, yet their long-term ecological effectiveness remains under-evaluated.
View Article and Find Full Text PDFEnviron Monit Assess
September 2025
Department of Geosciences, University of Bremen, Bremen, Germany.
Surveillance monitoring of shallow groundwater revealed that redox conditions can vary on a small scale. Therefore, the aim of this study was to categorize redox conditions in the groundwater of Lower Saxony, Germany, and to analyze the spatial distribution and trends of parameters related to redox conditions during surveillance monitoring from 1957 to 2015 in Lower Saxony, Germany. Methodically, trends were considered by applying the Mann-Kendall test and redox conditions of groundwater were classified according to the scheme of Jurgens et al.
View Article and Find Full Text PDFFunct Integr Genomics
September 2025
The First Clinical Medical College, Yunnan University of Chinese Medicine, Kunming, China.
Ischemic stroke (IS) has high morbidity/mortality with limited treatments. This study screened core copper homeostasis-related genes in IS and validated their function as precise intervention targets. Human IS gene chip data were retrieved from GEO, and copper homeostasis genes from multiple databases.
View Article and Find Full Text PDFChem Commun (Camb)
September 2025
School of Pharmacy, Nantong University, Nantong, Jiangsu Province, 226001, China.
In recent years, photosensitizer-based phototherapy has gained increasing attention in antibacterial applications due to its low cost, noninvasive nature, and low drug resistance. Among various materials, porphyrin-based metal-organic frameworks (MOFs) have demonstrated great potential, due to their good biocompatibility, facile designability, and excellent light absorption capabilities that enable highly efficient antibacterial efficacy. However, further optimization of their antibacterial performance remains a key challenge.
View Article and Find Full Text PDFCancer Med
September 2025
Department of Pulmonary Medicine, Saitama Medical Center, Saitama Medical University, Saitama, Japan.
Background: The prognosis of small-cell lung cancer (SCLC) remains poor, particularly in patients with extensive-stage SCLC. The IMpower133 and CASPIAN trials revealed the efficacy of immune checkpoint inhibitors (ICIs) in extensive-stage SCLC patients with good performance status (PS). The aim of this study was to investigate the efficacy of ICIs in patients with poor PS.
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