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Due to the constraints of the COVID-19 pandemic, healthcare workers have reported behaving in ways that are contrary to their values, which may result in distress and injury. This work is the first of its kind to evaluate the presence of stress in the COVID-19 VR Healthcare Simulation for Distress dataset. The dataset collected passive physiological signals and active mental health questionnaires. This paper focuses on correlating electrocardiogram, respiration, photoplethysmography, and galvanic skin response with the Perceived Stress Scale (PSS)-10 questionnaire. The analysis involved data-driven techniques for a robust evaluation of stress among participants. Low-complexity pre-processing and feature extraction techniques were applied and support vector machine and decision tree models were created to predict the PSS-10 scores of users. Imbalanced data classification techniques were used to further enhance our understanding of the results. Decision tree with oversampling through Synthetic Minority Oversampling Technique achieved an accuracy, precision, recall, and F1 of 93.50%, 93.41%, 93.31%, and 93.35%, respectively. Our findings offer novel results and clinically valuable insights for stress detection and potential for translation to edge computing applications to enhance privacy, longitudinal monitoring, and simplify device requirements.
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http://dx.doi.org/10.1109/EMBC40787.2023.10340958 | DOI Listing |
Epigenomics
September 2025
College of Physical Education, Yangzhou University, Yangzhou, China.
Background: Autism spectrum disorder (ASD) is a complex neurodevelopmental disorder lacking objective biomarkers for early diagnosis. DNA methylation is a promising epigenetic marker, and machine learning offers a data-driven classification approach. However, few studies have examined whole-blood, genome-wide DNA methylation profiles for ASD diagnosis in school-aged children.
View Article and Find Full Text PDFBMJ Public Health
September 2025
Affiliated to Wenzhou Medical University, Evidence-Based Medicine Center, Taizhou Hospital of Zhejiang Province, Linhai, China.
Objective: The aim of this study is to analyse the factors affecting medical burnout in hospitals, identify the characteristics of staff experiencing high levels of burnout and devise a practical and sustainable prediction mechanism.
Methods: A survey was conducted to access the current situation, followed by a regression analysis using data from the Maslach Burnout Inventory General Survey, demographic information related to healthcare personnel and employee job satisfaction metrics from the hospitals under study. Subsequently, four predictive models-logistic regression, K-nearest neighbour, decision tree and random forest (RF)-were employed to predict the degree of healthcare burnout.
Food Res Int
November 2025
College of Food Science and Engineering, Ocean University of China, Qingdao 266000, China; Inner Mongolia National Center of Technology Innovation for Dairy, Hohhot 150100, China. Electronic address:
The complexity of cheese flavour components, different origin and variability in experimental data have hindered credible flavour description of Cheddar cheese at different ripening time periods. This study combined GC-MS with machine learning to explore the common characteristic ingredients of Cheddar cheese independent of origin during ripening stage at 6-12 °C. A random forest model among six classifiers performed best in assessing Cheddar cheese ripening time and 14 flavour substances (ketones, acids, and lactones) were selected as characteristic flavours by recursive feature elimination from 66 flavour substances to train the model.
View Article and Find Full Text PDFRadiother Oncol
September 2025
Department of Radiation Oncology, National Cancer Center/National Clinical Research Center for Cancer/Cancer Hospital, Chinese Academy of Medical Sciences and Peking Union Medical College, Beijing 100021, China. Electronic address:
Purpose: Esophageal RV25 < 20 % and AV35 < 0.27 mL were reported as dose constraints predictive of grade ≥ 2 radiation esophagitis (RE) for breast cancer in our previous study. This prospective study aimed to validate the effectiveness of esophageal dose constraints and develop RE prediction models.
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