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The wide applications of terahertz (THz) wave technology in the ∼1-3 THz range has resulted in a surge in the demand for the performance improvement of THz wave detection technique. In this study, a frequency tunable, highly sensitive frequency upconversion detection based on a 2-(3-(4-hydroxystyryl)-5,5-dime-thylcyclohex-2-enylidene) malononitrile (OH1) crystal at room temperature is demonstrated. Moreover, to effectively increase the signal-to-noise ratio in the low frequency range, a beam isolation enhancer is proposed and its effect is verified. The minimum detectable THz pulse energy reaches about 100 aJ at 1.9 THz. The frequency tuning ranging from 1 to 3 THz. Sensitivity comparison with a 4-dimethylamino-N-methyl-4-stilbazolium tosylate (DAST) crystal system shows that OH1 is a more suitable nonlinear crystal in the 1-2.4 THz range.
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http://dx.doi.org/10.1364/OE.505363 | DOI Listing |
PLoS Comput Biol
September 2025
Program of Computational Sciences, Bard College, Annandale-on-Hudson, New York, United States of America.
Agent-based models (ABMs) have become essential tools for simulating complex biological, ecological, and social systems where emergent behaviors arise from the interactions among individual agents. Quantifying uncertainty through global sensitivity analysis is crucial for assessing the robustness and reliability of ABM predictions. However, most global sensitivity methods demand substantial computational resources, making them impractical for highly complex models.
View Article and Find Full Text PDFJ Infect Dev Ctries
August 2025
Division of Epidemiology and Biostatistics, Global Health Department, Faculty of Medicine and Health Sciences, Stellenbosch University, Cape Town, South Africa.
Introduction: Severe bacterial infections cause significant disease burden in developing countries, including Malawi. The situation is compounded by the scarcity of resources, inconsistent availability of antibiotics, and increasing antimicrobial resistance (AMR).
Methodology: This was a descriptive retrospective study where we analyzed blood culture results of pediatric patients admitted to Kamuzu Central Hospital (KCH), Lilongwe, Malawi.
PLoS One
September 2025
Faculty of Environmental, Climate Change and Urban Studies, National Economics University (NEU), Hanoi, Vietnam.
This study aims to assess the livelihood vulnerability to climate change of ethnic minority communities in Yen Bai province, a typical mountainous region in northern Vietnam. Utilizing the Livelihood Vulnerability Index (LVI) framework developed by Hahn et al. (2009), in combination with the IPCC vulnerability structure, the research analyzes eight components related to household characteristics, health, food, water, housing and productive land, social and financial networks, livelihood strategies, and exposure to climate shocks.
View Article and Find Full Text PDFJ Vis Exp
August 2025
Department of Nutritional Sciences, University of Wisconsin-Madison;
The retinol isotope dilution (RID) test is the most sensitive method to assess vitamin A status by estimating total liver reserves, considered the reference standard. For gas chromatography-combustion-isotope ratio mass spectrometry detection, C is added to the retinol moiety. The synthetic procedure for C-retinyl acetate begins with the naturally occurring β-ionone.
View Article and Find Full Text PDFInt J Biometeorol
September 2025
Key Laboratory of Land Surface Pattern and Simulation, Institute of Geographic Sciences and Natural Resources Research, Chinese Academy of Sciences, Beijing, 100101, China.
Plant viewing activities, which encompass the enjoyment of seasonal plant phenomena such as flowering and autumn leaf coloration, have become popular worldwide. Plant viewing activities are increasingly challenged by climate change, as key components like plant phenology and climate comfort are highly sensitive to global warming. However, few studies have explored the impact of climate change on viewing activities, particularly from an integrated, multi-factor perspective.
View Article and Find Full Text PDF