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Background: Research is essential for advancing medical knowledge and improving patient care. However, research capacity and output are low in low- and middle-income countries due to various challenges, including a lack of research training among medical students. Integrating research training into undergraduate medical curricula can help address this issue.
Methods: A cross-sectional study was conducted between December 2022 and March 2023 among 462 undergraduate medical students at Tanta University, Egypt to assess their knowledge, attitudes, and perceived barriers toward conducting research. Data were collected using a self-administered questionnaire and analyzed using SPSS.
Results: Nearly half (49.8%) of the students had an acceptable level of knowledge about research concepts while over two-thirds (66.2%) had a positive attitude. The most common barriers were lack of funding, time, and training in research methods. Previous research training was reported by 66.7% of students, but less than half had participated in or presented research. Students in the competency-based program had significantly higher knowledge and more positive attitudes than those in the mainstream program. Knowledge level was positively correlated with attitude.
Conclusion: While attitudes were generally positive, improvements are needed in research training and opportunities among undergraduate medical students at Tanta University to help address low research capacity challenges in low- and middle-income countries. Integration of formal research training into the curriculum may help increase knowledge and participation in research.
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http://dx.doi.org/10.1186/s12909-023-04884-z | DOI Listing |
Aquac Nutr
August 2025
Faculty of Agriculture, Tanta University, Tanta 31527, Egypt.
Aquaculture and animal producers are increasingly exploring natural additives such as for their health-promoting and sustainability-enhancing roles. Known primarily as a sweetener, also contains bioactive compounds, such as stevioside and rebaudioside A (Reb A), which exhibit antibacterial, antioxidant, immunomodulatory, and metabolic benefits. Recent studies suggest that these compounds may also exert prebiotic-like activities by modulating the gut microbiota, promoting the growth of beneficial bacterial populations (e.
View Article and Find Full Text PDFFront Immunol
September 2025
Department of Biology, College of Science, United Arab Emirates University, Al Ain, United Arab Emirates.
Curcumin (1,7-bis-(4-hydroxy-3-methoxyphenyl)-hepta-1,6-diene-3,5-dione) is a naturally occurring polyphenol molecule. It is lipophilic and has demonstrated and therapeutic effects through multiple pathways. Extensive studies on its pharmacological properties have shown its anti-inflammatory, antioxidant, antinociceptive, antimicrobial, antiparasitic, antimalarial, and wound-healing properties.
View Article and Find Full Text PDFJ Palliat Med
September 2025
Middle East Cancer Consortium, Haifa, Israel.
Despite a plethora of evidence available on the benefits of palliative care (PC), it is estimated that only about 14% of those living in low- to middle-income countries (LMIC) or developing countries have access to PC. To globally examine PC expert perspectives regarding PC infrastructure and resources within each country, drug and opioid availability to provide PC, and workforce and educational issues. Descriptive, open-ended survey seeking first-hand qualitative perspectives.
View Article and Find Full Text PDFNeuromodulation
September 2025
Department of Neurological Surgery, Oregon Health & Science University, Portland, OR, USA. Electronic address:
Objective: This systematic review and meta-analysis evaluates the efficacy of bilateral subthalamic nucleus (STN) deep brain stimulation (DBS) in improving gastric motility in patients with Parkinson's disease (PD).
Materials And Methods: A systematic search was conducted in Scopus, Web of Science, PubMed, and Cochrane CENTRAL until December 15, 2024. Observational studies and clinical trials evaluating DBS effects on gastric motility and gastric emptying in patients with PD were included.
J Pharmacokinet Pharmacodyn
September 2025
Centre for Applied Pharmacokinetic Research (CAPKR), University of Manchester, Manchester, UK.
Concentration-dependent binding to red blood cells is a characteristic of several drugs, complicating the understanding of how pathophysiological factors influence drug behavior. This study utilized user-friendly, physiologically-based pharmacokinetic (PBPK) models to compare concentration-dependent and independent blood-to-plasma drug concentration ratios (B/P), using tacrolimus as a case study. Two models were developed and validated for tacrolimus using clinical data from healthy volunteers; Model 1 accounted for saturable blood binding, and Model 2 used a constant B/P level.
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