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http://dx.doi.org/10.1016/j.tjnut.2023.11.008 | DOI Listing |
Front Insect Sci
August 2025
Department of Life Sciences and Systems Biology (DBIOS), University of Turin, Turin, Italy.
Dung beetles (Coleoptera, Scarabaeoidea) support several ecological processes and services making them important ecosystem engineers. The dung beetle gut microbiota is involved in many of these ecological services. In the present study, we analyzed the microbiota of 90 individuals of three species feeding on different dung types.
View Article and Find Full Text PDFFront Immunol
September 2025
Drug Discovery Department, Enterome, Paris, France.
Background: Advancing research in oncology highlights the inverse correlation between antibiotic treatment and the positive outcomes of immune checkpoint inhibitor (ICI) administration, confirming once more the importance of microbiota and microbiota-derived compounds as complementary tools for treating cancer. Among the immune checkpoints, the CD200 cell surface glycoprotein has gained attention for its role in promoting self-tolerance and potentially facilitating tumor growth through interaction with the CD200R1 receptor.
Methods: We developed a robust AlphaLISA-based screening to identify human gut microbiota-derived proteins that may interact with CD200R1 and screened a library of 10,966 gut bacterial proteins.
Technol Cancer Res Treat
August 2025
Physiology Research Center, Iran University of Medical Sciences, Tehran, Iran.
IntroductionImmunotherapy approaches have improved by Immune check point inhibitors such as PD-1, CTLA-4, and PD-L1 inhibitors. However, the response to immunotherapy varies widely among patients due to various factors. Co-administration of probiotics with ICIs has become a promising strategy to improve therapeutic outcomes.
View Article and Find Full Text PDFVet Sci
August 2025
Department of Veterinary Sciences, School of Agriculture and Veterinary Medicine, University of Turin, 10095 Turin, Italy.
Hydrolyzed protein is increasingly used in pet food, especially for animals with adverse reactions to food or gastrointestinal issues. This randomized, double-blind controlled trial evaluated the effects of a diet containing hydrolyzed anchovy protein on the gut health of healthy adult West Highland white terriers (5 males, 25 females; 5.6-9 kg).
View Article and Find Full Text PDFFront Microbiol
August 2025
Fujian University of Traditional Chinese Medicine, Fuzhou, China.
Objective: The primary objective of this study was to assess the impact of fecal microbiota transplantation (FMT) on serum biochemical parameters, renal injury, and gut microbiota in hyperuricemia (HUA) mice.
Methods: Six-week-old male C57BL/6 J mice were given a high-purine diet and potassium oxonate injections to induce HUA, followed by a two-week FMT treatment. Regular body weight checks, serum biochemical analyses, and fecal sampling for 16S rRNA gene sequencing were conducted to evaluate the treatment's impact on gut microbiota.