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Article Abstract

The gene encodes a secreted protein, and the gene is a member of the transcription factor family. Both genes have multiple biological functions. This study was conducted to investigate the association between and gene polymorphisms and wool fiber diameter and to determine potential molecular marker sites for breeding sheep with fine wool. We used Kompetitive Allele-Specific PCR to type the single nucleotide polymorphism (SNP) loci in the and genes within 1081 Alpine Merino sheep and associated these SNPs with wool fiber diameter. The results revealed one SNP in and , which were each related to sheep fiber diameter. The wool fiber diameters of sheep with the CC genotype in g.478807C>G and AA genotype in g.677G>A were the smallest and differed significantly from the diameters of other genotypes ( < 0.05). These results suggest potential molecular marker sites for fine-wool sheep breeding.

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http://www.ncbi.nlm.nih.gov/pmc/articles/PMC10668676PMC
http://dx.doi.org/10.3390/ani13223552DOI Listing

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