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Objective: This study aims to investigate the clinical efficacy of stereotactic puncture for intracerebral hematoma removal, combined with postoperative individualized health education and rehabilitation training concerning hypertensive cerebral hemorrhage. We also assessed its impact on rebleeding prevention and neurological function recovery.
Methods: A retrospective study was conducted, including 90 patients diagnosed with hypertensive cerebral hemorrhage in our hospital between March 2020 and June 2022. The inclusion criteria were patients with an episcleral hematoma volume exceeding 30 ml. The control group underwent minimally invasive removal using neuroendoscopy (45 patients), while the observation group received stereotactic puncture for intracerebral hematoma removal (45 patients). After surgery, both groups received individualized health education and rehabilitation training. The assessment included: (1) determination of clinical efficacy, (2) monitoring for rebleeding within 72 hours after surgery, (3) evaluation of daily living ability using the Barthel index, (4) assessment of motor function using the Fugl-Meyer Assessment (FMA) scale, and (5) monitoring for adverse reactions.
Results: The observation group, which underwent stereotactic puncture for intracerebral hematoma removal combined with postoperative individualized health education and rehabilitation training, exhibited significantly better clinical efficacy, Barthel index scores, and FMA scores compared to the control group that underwent neuroendoscopic minimally invasive removal (P < .05). Notably, no complications were observed in either group, and there was no significant difference in the postoperative bleeding rate within 72 hours.
Conclusions: The combined treatment approach of stereotactic puncture for intracerebral hematoma removal and postoperative individualized health education and rehabilitation training demonstrates promising therapeutic effects in managing hypertensive cerebral hemorrhage. This approach also contributes significantly to the rehabilitation of patients with hypertensive cerebral hemorrhage, warranting widespread clinical adoption.
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Cureus
July 2025
Neuro-Oncology, Instituto Nacional de Cancerología, Mexico City, MEX.
Background: Primary central nervous system lymphoma (PCNSL) remains a diagnostic challenge due to its radiological overlap with other brain lesions and limitations of stereotactic biopsy, particularly following corticosteroid exposure. Interleukin-10 (IL-10) is a cytokine frequently elevated in PCNSL and has emerged as a potential diagnostic biomarker, yet reported cut-off values vary widely, limiting clinical application.
Objective: To determine the diagnostic accuracy of CSF IL-10 for differentiating PCNSL from other brain lesions by estimating the optimal cut-off, sensitivity, specificity, and area under the receiver operating characteristic (ROC) curve (AUC), and to explore its potential prognostic value.
World Neurosurg
August 2025
Department of Neurosurgery, Huashan Hospital, Shanghai Medical College, Fudan University, Shanghai, China. Electronic address:
Objective: To evaluate the feasibility and efficacy of a simplified surface-based localization technique, utilizing the bregma-preauricular depression axis, for basal ganglia hematoma evacuation via the middle frontal gyrus surgical approach.
Methods: A retrospective analysis was conducted on 33 cases of basal ganglia intracerebral hemorrhage treated between January and December 2024. All procedures were performed via the middle frontal gyrus.
Front Neurol
July 2025
Department of Neurosurgery, The First People's Hospital of Yibin, Yibin, Sichuan, China.
Background: Hypertensive basal ganglia haemorrhage (HBGH) is a prevalent critical condition in neurosurgery characterised. Severe neurologic dysfunctional outcome despite systemic treatment. The objective of this study is to examine the impact of stereotactic minimally invasive puncture and drainage utilising DTI on the efficacy and quality of life of patients diagnosed with moderate-volume HBGH.
View Article and Find Full Text PDFStroke Vasc Neurol
August 2025
Department of Neurosurgery, Beijing Tiantan Hospital, Capital Medical University, Beijing, China
Introduction: Minimally invasive puncture surgery followed by thrombolysis has been proven to be an effective approach for managing hypertensive intracerebral haemorrhage (ICH). Nevertheless, its impact on improving neurological outcomes remains controversial. The integration of neuronavigation-assisted stereotactic (NAS) technology will significantly help enhance the accuracy of catheter placement, while tenecteplase (TNK), a third-generation thrombolytic agent, offers stronger capabilities in breaking down platelet-rich clots and demonstrates increased fibrin selectivity, which could enhance the overall effectiveness of thrombolytic treatment.
View Article and Find Full Text PDFZhongguo Yi Liao Qi Xie Za Zhi
May 2025
National United Engineering Laboratory for Biomedical Material Modification, Dezhou, 251100.
Insertion of external ventricular drainage (EVD) is an effective neurosurgical treatment approach. The accuracy of EVD insertion is related to potential complications, and the precise placement of the catheter tip can reduce the incidence of complications. With the progress of medical technology, the research and application of EVD catheterization technology are developing rapidly.
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