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Background: Economic hardships imposed by the pandemic could have implications for children's experiences of adversity in the home, or Adverse Childhood Experiences (ACEs).
Objective: This observational cohort study examined associations between COVID-19-related hardships and distress (e.g., job loss, caregiver stress) and the cumulative number of child ACEs reported by caregivers during the pandemic (i.e., March 1, 2020-February 28, 2022).
Participants And Setting: The study included children (N = 4345; median age = 6.0 years, interquartile range = 4-9 years) and their parents/caregivers who participated in the NIH-funded Environmental influences in Child Health Outcomes (ECHO) Program.
Methods: We described socio-demographic characteristics and pandemic-related family hardships/distress and cumulative child ACE scores reported during pre-pandemic and pandemic periods. We used negative binomial regression models to evaluate associations between pandemic-related family hardships and cumulative child ACE scores reported during the pandemic.
Results: Each caregiver-reported hardship/distress was associated with higher child ACE scores reported during the pandemic. After accounting for pre-pandemic child ACE scores, moderate and severe symptoms of pandemic-related traumatic stress among caregivers were associated with 108 % and 141 % higher child ACE scores reported during the pandemic, respectively, compared with no or low caregiver symptoms. In addition, finance-related stress during the pandemic was associated with 47 % higher child ACE scores. After adjusting for pre-pandemic child experiences of neglect, most sources of stress remained significantly associated with higher child ACE scores reported during the pandemic, particularly severe/very severe symptoms of pandemic-related traumatic stress among caregivers. Findings held for children with no known pre-pandemic ACEs.
Conclusions: This research suggests that caregivers experiencing financial hardships and those with severe pandemic-related traumatic stress may require additional support systems during stressful events.
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http://www.ncbi.nlm.nih.gov/pmc/articles/PMC11338313 | PMC |
http://dx.doi.org/10.1016/j.chiabu.2023.106510 | DOI Listing |
J Interpers Violence
September 2025
University of Oregon, Eugene, OR, USA.
Trauma-informed communication has shown promise in healthcare settings for supporting individuals affected by adverse childhood experiences (ACEs), yet its application in public health messaging remains underexplored. Given the strong link between ACEs and intimate partner violence victimization (IPVV), this study designed and tested a trauma-informed, text-based message aimed at promoting trauma understanding and positive behavioral intentions among women experiencing IPVV with self-reported ACEs. The message incorporated two core trauma-informed components-psychoeducation and empowerment-and was evaluated against a conventional IPVV message in a randomized controlled trial ( = 289).
View Article and Find Full Text PDFJ Affect Disord
September 2025
School of Medicine, University of Virginia, Charlottesville, VA, USA.
Postpartum depression (PPD) is a major public health issue, significantly affecting the health and well-being of women and children. Research indicates a strong link between adverse childhood experiences (ACEs) and increased PPD rates. While the Adverse Childhood Experiences Questionnaire (ACE-Q) is widely used for ACE screening, the Childhood Traumatic Events Scale (CTES) may better capture trauma items not covered by the ACE-Q, along with the timing and severity of ACEs.
View Article and Find Full Text PDFJ Affect Disord
September 2025
Department of Counseling, College of Education, Health, and Human Science, University of Nebraska Omaha, United States of America. Electronic address:
Background: Adverse Childhood Experiences (ACEs) and Positive Childhood Experiences (PCEs) play critical roles in adolescent mental health, influencing onset and recovery. Informed by the Social-Ecological Risk and Protective Factors framework, the current study examines ACEs as barriers and PCEs as facilitators in recovery from anxiety and depression. We used continuous score and categorical subgroup models to capture both linear and potential threshold effects.
View Article and Find Full Text PDFCurr Hypertens Rev
August 2025
Global Research Institute of Pharmacy, Radaur, Yamuna Nagar, 135133, Haryana, India.
Pediatric hypertension (PH) is an emerging global public health issue, increasingly linked to genetic, environmental, and lifestyle factors. Early-onset hypertension is associated with progressive long-term cardiovascular problems. This overview outlines the epidemiology, etiology, pathophysiology, treatment modalities, and current clinical studies related to hypertension in children and adolescents.
View Article and Find Full Text PDFThorax
September 2025
Clinical Trials Accelerator Platform, London, UK
A common eligibility criterion in respiratory clinical trials is a per cent-predicted forced expiratory volume in 1 second (ppFEV) between 40% and 90%, using the ethnicity-dependent Global Lung Function Initiative (GLI)-2012 spirometry reference equations. International societies now endorse the newer 'race-neutral' GLI-Global equations. We quantify the impact on trial eligibility of switching from GLI-2012 to GLI-Global for the UK Cystic Fibrosis Registry (n=8182).
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